ArticleJournal of proteome research2020
Measurement of Organ-Specific and Acute-Phase Blood Protein Levels in Early Lyme Disease.
Open access · greenAbstract readMulticenter Study
In one paragraph
Article in Journal of proteome research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- Borrelia burgdorferi disrupts gut barrier functions and microbiota-antibody interactions.The Journal of experimental medicine · 2026Article
- From forest floor to doctor's office: the immunological journey ofFrontiers in immunology · 2026Review
- Research on the role and mechanisms of Cystatin 6 in disease pathosis and development.Frontiers in molecular biosciences · 2026Review
- The role of digital twins in P4 medicine: A paradigm for modern healthcare.NPJ digital medicine · 2025Review
- Insights From Omics in Lyme Disease.The Journal of infectious diseases · 2024Review
- Low-Abundance Protein Enrichment for Medical Applications: The Involvement of Combinatorial Peptide Library Technique.International journal of molecular sciences · 2023Review
- Large-Scale Sequencing ofGenes · 2022Review
- Longitudinal serum proteomics analyses identify unique and overlapping host response pathways in Lyme disease and West Nile virus infection.Frontiers in immunology · 2022Article
- Article
- Article
- Toxic Metal Species and 'Endogenous' Metalloproteins at the Blood-Organ Interface: Analytical and Bioinorganic Aspects.Molecules (Basel, Switzerland) · 2021Article
- Review
- Laboratory Diagnosis of Lyme Borreliosis.Clinical microbiology reviews · 2021Review
- Lyme Disease in Humans.Current issues in molecular biology · 2021Article
- Recent Progress in Lyme Disease and Remaining Challenges.Frontiers in medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 7 institutions in 3 countries.
Yong ZhouInstitute for Systems Biology , Seattle , Washington 98109 , United States.ORCID 0000-0001-7643-5455
Shizhen QinInstitute for Systems Biology , Seattle , Washington 98109 , United States.
Mingjuan SunInstitute for Systems Biology , Seattle , Washington 98109 , United States.
Li TangInstitute for Systems Biology , Seattle , Washington 98109 , United States.
Xiaowei YanInstitute for Systems Biology , Seattle , Washington 98109 , United States.
Taek-Kyun KimInstitute for Systems Biology , Seattle , Washington 98109 , United States.
Juan CaballeroMolecular and Developmental Complexity Lab , Langebio-Cinvestav , Irapuato , Guanajuato 36821 , Mexico.
Gustavo GlusmanInstitute for Systems Biology , Seattle , Washington 98109 , United States.
Mary E BrunkowInstitute for Systems Biology , Seattle , Washington 98109 , United States.
Mark J SoloskiLyme Disease Research Center, Division of Rheumatology, Department of Medicine , Johns Hopkins University School of Medicine , Baltimore , Maryland 21093 , United States.
Alison W RebmanLyme Disease Research Center, Division of Rheumatology, Department of Medicine , Johns Hopkins University School of Medicine , Baltimore , Maryland 21093 , United States.
Carol ScavardaDivision of Infectious Diseases, Department of Medicine , New York Medical College , Valhalla , New York 10595 , United States.
Denise CooperDivision of Infectious Diseases, Department of Medicine , New York Medical College , Valhalla , New York 10595 , United States.
Gilbert S OmennInstitute for Systems Biology , Seattle , Washington 98109 , United States.ORCID 0000-0002-8976-6074
Robert L MoritzInstitute for Systems Biology , Seattle , Washington 98109 , United States.ORCID 0000-0002-3216-9447
Gary P WormserDivision of Infectious Diseases, Department of Medicine , New York Medical College , Valhalla , New York 10595 , United States.
Nathan D PriceInstitute for Systems Biology , Seattle , Washington 98109 , United States.
John N AucottLyme Disease Research Center, Division of Rheumatology, Department of Medicine , Johns Hopkins University School of Medicine , Baltimore , Maryland 21093 , United States.
Leroy HoodInstitute for Systems Biology , Seattle , Washington 98109 , United States.
Institute for Systems Biology · USJohns Hopkins University · USNew York Medical College · USCentro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MXProvidence College · USSecond Military Medical University · CNUniversity of Michigan · US
Funding
Quantitative Systems BiologyP50GM076547 · NIGMS · INSTITUTE FOR SYSTEMS BIOLOGY · PI DUDLEY, AIMEE M · 2006 to 2016
$30.6MStrategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3MSample Processing and Immunoassay Research CoreP30AR070254 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI CLIFTON O BINGHAM, Antony Rosen · 2016 to 2026
$8.9MPhenotype-Specific Immune Responses in the Systemic VasculitidesP30AR053503 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI ROSEN, ANTONY · 2006 to 2015
$6.4MUniversity of Michigan Proteogenomics Data Analysis CenterU24CA210967 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHINNAIYAN, ARUL M, DHANASEKARAN, SARAVANA M · 2016 to 2020
$4.1MProteogenomic resource for the development of novel markers for Lyme diseaseR21AI142302 · NIAID · INSTITUTE FOR SYSTEMS BIOLOGY · PI MORITZ, ROBERT L · 2019 to 2020
$522kNovel peptide based biomarkers for Lyme disease diagnosticsR21AI133335 · NIAID · INSTITUTE FOR SYSTEMS BIOLOGY · PI MORITZ, ROBERT L · 2018 to 2019
$522kNCI NIH HHS U24 CA210967NIAID NIH HHS R21 AI133335NIAID NIH HHS R21 AI142302NIAMS NIH HHS P30 AR053503NIAMS NIH HHS P30 AR070254NIEHS NIH HHS P30 ES017885NIGMS NIH HHS P50 GM076547
Abstract
Lyme disease results from infection of humans with the spirochete
Indexed as
Acute-Phase ProteinsAdultAgedBiomarkersBlotting, WesternCase-Control StudiesErythema Chronicum MigransFemaleHumansImmunity, InnateLyme DiseaseMaleMiddle AgedMultivariate AnalysisOrgan SpecificityAcute-Phase ProteinsBiomarkersacute phase proteinLyme diseaseorgan-specific proteinproteomicsselective reaction monitoringSRMtick-borne disease
Identifiers
What OpenQuestion holds
Textmetadata
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.