Evidence map›Paper›PMID 31618094›Full record

ArticleToxicology mechanisms and methods2020

A multiparametric organ toxicity predictor for drug discovery.

Chirag N Patel, Sivakumar Prasanth Kumar, Rakesh M Rawal, Daxesh P Patel, Frank J Gonzalez, Himanshu A Pandya

Open access · greenAbstract read
In one paragraph

Article in Toxicology mechanisms and methods, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Chirag N PatelDepartment of Botany, Bioinformatics and Climate Change Impacts Management, University School of Sciences, Gujarat University, Ahmedabad, India.ORCID http://orcid.org/0000-0002-0167-8708
Sivakumar Prasanth KumarDivision of Biological Sciences, Molecular Biophysics Unit, Indian Institute of Science (IISc), Bangalore, India.ORCID http://orcid.org/0000-0003-3461-2489
Rakesh M RawalDepartment of Life Sciences, University School of Sciences, Gujarat University, Ahmedabad, India.ORCID http://orcid.org/0000-0002-7985-1187
Daxesh P PatelLaboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Frank J GonzalezLaboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.ORCID http://orcid.org/0000-0002-7990-2140
Himanshu A PandyaDepartment of Botany, Bioinformatics and Climate Change Impacts Management, University School of Sciences, Gujarat University, Ahmedabad, India.ORCID http://orcid.org/0000-0003-4536-9541
Gujarat University · INNational Institutes of Health · USIndian Institute of Science Bangalore · IN

Funding

Xenobiotic ReceptorsZIABC005708 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI GONZALEZ, FRANK J · 2009 to 2025
$16.4M
Intramural NIH HHS ZIA BC005708
6 · The paper itself

Abstract

The assessment of major organ toxicities through

Indexed as

Drug DiscoveryAnimalsHumansModels, StatisticalOrgan SpecificityQuantitative Structure-Activity RelationshipToxicity Testsin silicomultiparametric approachOrgan toxicitiesphysico-chemical properties

Identifiers

PMID31618094
PMCPMC7383222
OpenAlexW2981017551

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.