ReviewEnvironmental health perspectives2019
Evidence for Bisphenol B Endocrine Properties: Scientific and Regulatory Perspectives.
Review in Environmental health perspectives, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 100 citations in OpenAlex.
- Sustainable Diepoxide Monomers for Polyoxazolidinone-Based High-Performance Thermoplastics.ChemSusChem · 2026Article
- An Integrated Approach Combining Regulatory Tests inEnvironmental science & technology · 2026Article
- Bisphenol A and its analogues in thyroid diseases: Evidence from dysfunction, autoimmunity, and cancer.iScience · 2026Review
- Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Elucidating the mechanisms of bisphenols-induced male spermatogenesis disorder via network toxicology, molecular docking and bioinformatics.BMC medical genomics · 2026Article
- From toxicogenomics data to cumulative assessment groups: a framework for chemical grouping.Archives of toxicology · 2026Article
- Exposure to Bisphenol B and S Increases the Risk of Male Reproductive Dysfunction in Middle Age.International journal of molecular sciences · 2025Article
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- Mitigating Dietary Bisphenol Exposure Through the Gut Microbiota: The Role of Next-Generation Probiotics in Bacterial Detoxification.Nutrients · 2024Review
- Bisphenol A and its analogues: from their occurrence in foodstuffs marketed in Europe to improved monitoring strategies-a review of published literature from 2018 to 2023.Archives of toxicology · 2024Review
- Endocrine-disrupting chemical concentrations in follicular fluid and follicular reproductive hormone levels.Journal of assisted reproduction and genetics · 2024Article
- Structural Studies on the Binding Mode of Bisphenols to PPARγ.Biomolecules · 2024Article
- Comparison of the Effect of BPA and Related Bisphenols on Membrane Integrity, Mitochondrial Activity, and Steroidogenesis of H295R Cells In Vitro.Life (Basel, Switzerland) · 2023Article
- Invisible Hand behind Female Reproductive Disorders: Bisphenols, Recent Evidence and Future Perspectives.Toxics · 2023Review
- Maternal Bisphenol B Exposure and Mammary Gland Development of Offspring: A Time-Series Analysis.Environment & health (Washington, D.C.) · 2023Article
- Origin, dietary exposure, and toxicity of endocrine-disrupting food chemical contaminants: A comprehensive review.Heliyon · 2023Article
- Predicting Endocrine Disruption Using Conformal Prediction - A Prioritization Strategy to Identify Hazardous Chemicals with Confidence.Chemical research in toxicology · 2023Article
- Lifestyle interventions to reduce endocrine-disrupting phthalate and phenol exposures among reproductive age men and women: A review and future steps.Environment international · 2022Review
- What Does CLARITY-BPA Mean for Canadians?International journal of environmental research and public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe substitution of bisphenol A (BPA) by bisphenol B (BPB), a very close structural analog, stresses the need to assess its potential endocrine properties.
objectiveThis analysis aimed to investigate whether BPB has endocrine disruptive properties in humans and in wildlife as defined by the World Health Organization (WHO) definition used in the regulatory field, that is,
methodsWe conducted a systematic review to identify BPB adverse effects and endocrine activities by focusing on animal models and
resultsAmong the 36 articles included in the analysis, 3 subchronic studies consistently reported effects of BPB on reproductive function. In rats, the 28-d and 48-week studies showed alteration of spermatogenesis associated with a lower height of the seminiferous tubules, the alteration of several sperm parameters, and a weight loss for the testis, epididymis, and seminal vesicles. In zebrafish, the results of a 21-d reproductive study demonstrated that exposed fish had a lower egg production and a lower hatching rate and viability. The
conclusionThe available
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.