Evidence map›Paper›PMID 31617748›Full record

ArticleDento maxillo facial radiology2020

Evaluation of treatment response in oral chronic graft-versus-host patients by power doppler ultrasound: a prospective study.

Yiqun Liu, Jiaan Zhu, Huijie Guo, Wenxue Li, Xiuming Wang, Zheng Chen, Fang Liu, Ariun Bilig

Open access · bronzeAbstract read
In one paragraph

Article in Dento maxillo facial radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yiqun LiuDepartment of Ultrasound, Peking University People's Hospital, 11 Xizhimen South Street, Beijing 100044, People's Republic of China.
Jiaan ZhuDepartment of Ultrasound, Peking University People's Hospital, 11 Xizhimen South Street, Beijing 100044, People's Republic of China.
Huijie GuoDepartment of Stomatology, Peking University People's Hospital, 11 Xizhimen South Street, Beijing 100044, People's Republic of China.
Wenxue LiDepartment of Ultrasound, Peking University People's Hospital, 11 Xizhimen South Street, Beijing 100044, People's Republic of China.
Xiuming WangDepartment of Ultrasound, Peking University People's Hospital, 11 Xizhimen South Street, Beijing 100044, People's Republic of China.
Zheng ChenDepartment of Ultrasound, Peking University People's Hospital, 11 Xizhimen South Street, Beijing 100044, People's Republic of China.
Fang LiuDepartment of Ultrasound, Peking University People's Hospital, 11 Xizhimen South Street, Beijing 100044, People's Republic of China.
Ariun BiligDepartment of Ultrasound, Peking University People's Hospital, 11 Xizhimen South Street, Beijing 100044, People's Republic of China.
Peking University People's Hospital · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo date, imaging and non-invasive examination methods for evaluating the oral tissue of patients who with oral chronic graft-versus-host disease (GVHD) are still lacking. Herein, we assessed the ultrasonography imaging characteristics of chronic GVHD patients' buccal soft tissue and evaluated the response to treatment using gray-scale and power Doppler (PD) ultrasound. The overall objective of the study was to determine the potential of ultrasonography to provide an early and objective indication of a therapeutic response to treatment intervention in oral chronic GVHD.

methodsBuccal mucosa in 21 patients with clinically diagnosis of oral chronic GVHD were assessed before and after 14 day treatment between 2016 and 2018. Ultrasonography assessment included thickness and echogenicity evaluation, and PD. Echogenicity and PD were measured and scored according to a semi-quantitative method. Ultrasonography parameters were compared with clinical activity assessments of disease activity and patient-reported measures.

resultsFollowing 14 day therapy, a significant decrease in PD scores and patient-reported measures was observed (

conclusionUltrasonography is a novel and feasible imaging technique for measurement of the response of oral chronic GVHD to therapy. Ultrasonography yields additional information about buccal mucosa and is a complementaty to clinical examination.

Indexed as

Graft vs Host DiseaseMouth DiseasesUltrasonography, DopplerChronic DiseaseHumansMouth MucosaProspective StudiesGraft-versus-host diseaseMouth mucosaUltrasonography

Identifiers

PMID31617748
PMCPMC7026929
OpenAlexW2981083996

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.