Evidence map›Paper›PMID 31617678›Full record

ArticleCNS neuroscience & therapeutics2020

Role of the PGE

James Catlin, Jenna L Leclerc, Krunal Shukla, Sarah M Marini, Sylvain Doré

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in CNS neuroscience & therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Role of the PGECNS neuroscience & therapeutics · 2020
    Article
  5. Traumatic brain injury.CNS neuroscience & therapeutics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

James CatlinDepartment of Anesthesiology, University of Florida, Gainesville, FL, USA.
Jenna L LeclercDepartment of Anesthesiology, University of Florida, Gainesville, FL, USA.
Krunal ShuklaDepartment of Anesthesiology, University of Florida, Gainesville, FL, USA.ORCID 0000-0002-5607-3036
Sarah M MariniDepartment of Anesthesiology, University of Florida, Gainesville, FL, USA.
Sylvain DoréDepartment of Anesthesiology, University of Florida, Gainesville, FL, USA.ORCID 0000-0003-3771-5109
University of Florida · US

Funding

Role of Prostaglandin Receptors in StrokeR01NS046400 · NINDS · UNIVERSITY OF FLORIDA · PI DORE, SYLVAIN · 2003 to 2014
$3.0M
CO therapeutic role and potential mechanism in TBIR21NS103036 · NINDS · UNIVERSITY OF FLORIDA · PI DORE, SYLVAIN · 2018 to 2019
$419k
NINDS NIH HHS R01 NS046400NINDS NIH HHS R21 NS103036
6 · The paper itself

Abstract

aimsThe goal was to explore the signaling pathways of PGE

methodsYoung (4.9 ± 1.0 months) and aged (20.4 ± 1.4 months) male wild type (WT) C57BL/6 and PGE

resultsNo differences in hippocampal microgliosis were found when aged EP2

conclusionThese findings demonstrate that the PGE

Indexed as

AnimalsBrain Injuries, TraumaticMaleMiceMice, Inbred C57BLMice, KnockoutReceptors, Prostaglandin EReceptors, Prostaglandin E, EP1 SubtypeReceptors, Prostaglandin E, EP2 SubtypeReceptors, Prostaglandin E, EP3 SubtypeReceptors, Prostaglandin EReceptors, Prostaglandin E, EP1 SubtypeReceptors, Prostaglandin E, EP2 SubtypeReceptors, Prostaglandin E, EP3 SubtypeconcussioneicosanoidsEP receptorsprostanoidsrepetitive head injury

Identifiers

PMID31617678
PMCPMC7248542
OpenAlexW2980488683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.