ArticleThe EMBO journal2020
Non-canonical AUX/IAA protein IAA33 competes with canonical AUX/IAA repressor IAA5 to negatively regulate auxin signaling.
Article in The EMBO journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.
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Who cites it
63 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Early "Rootprints" of Plant Terrestrialization: Selaginella Root Development Sheds Light on Root Evolution in Vascular Plants.Frontiers in plant science · 2021Pooled it
- GeARF5/GeIAA33-GeSWEET14 module balances the secondary metabolic biosynthesis to increase the yield and quality in Gastrodia elata.Journal of integrative plant biology · 2026Article
- Single-cell transcriptomic analysis of plant quiescent center by third-generation sequencing reveals developmental trajectories.Genome biology · 2026Article
- Genome-Wide Identification and Expression Profiling of theInternational journal of molecular sciences · 2025Article
- Auxin Biosynthesis, Transport, Signaling, and Its Roles in Plant Leaf Morphogenesis.Plants (Basel, Switzerland) · 2025Review
- Synthetic microbial community in pristine environment promotes the growth of the endangered plant Lilium tsingtauense.Microbiome · 2025Article
- Aux/IAAs: specificity and redundancy.Plant signaling & behavior · 2025Review
- PtrIAA12-PtrARF8 Complex Regulates the Expression ofPlants (Basel, Switzerland) · 2025Article
- Phenotypic plasticity in maize grain yield: Genetic and environmental insights of response to environmental gradients.The plant genome · 2025Article
- Out of the Niche: A Bird's-Eye View of the Molecular Networks Controlling Root Stem Cells.Plants (Basel, Switzerland) · 2025Review
- 6-Hydroxynicotinic Acid From Cucumis melo Inhibits Prehaustorium Formation in Phelipanche aegyptiaca via Disruption of Auxin Signalling Pathway.Molecular plant pathology · 2025Article
- Expression analyses of sweet cherry AUX/IAAs and involvements of PavAUX/IAA9/11 in regulating fruitlet abscission.Plant cell reports · 2025Article
- Genome-wide identification and salt stress-responsive expression profiling of Aux/IAA gene family in Asparagus officinalis.BMC plant biology · 2025Article
- Exogenous GAPlants (Basel, Switzerland) · 2025Article
- Transcriptome Analysis ofInternational journal of molecular sciences · 2025Article
- Phosphorylation of auxin signaling repressor IAA8 by heat-responsive MPKs causes defective flower development.Plant physiology · 2024Article
- A gain-of-function mutation in BnaIAA13 disrupts vascular tissue and lateral root development in Brassica napus.Journal of experimental botany · 2024Article
- VIK-Mediated Auxin Signaling Regulates Lateral Root Development in Arabidopsis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Single-cell network analysis reveals gene expression programs for Arabidopsis root development and metabolism.Plant communications · 2024Article
- The MKK3 MAPK cascade integrates temperature and after-ripening signals to modulate seed germination.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
3 more citing papers are in PubMed but not listed here.
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Authors and funding
13 authors.
Funding
Abstract
The phytohormone auxin controls plant growth and development via TIR1-dependent protein degradation of canonical AUX/IAA proteins, which normally repress the activity of auxin response transcription factors (ARFs). IAA33 is a non-canonical AUX/IAA protein lacking a TIR1-binding domain, and its role in auxin signaling and plant development is not well understood. Here, we show that IAA33 maintains root distal stem cell identity and negatively regulates auxin signaling by interacting with ARF10 and ARF16. IAA33 competes with the canonical AUX/IAA repressor IAA5 for binding to ARF10/16 to protect them from IAA5-mediated inhibition. In contrast to auxin-dependent degradation of canonical AUX/IAA proteins, auxin stabilizes IAA33 protein via MITOGEN-ACTIVATED PROTEIN KINASE 14 (MPK14) and does not affect IAA33 gene expression. Taken together, this study provides insight into the molecular functions of non-canonical AUX/IAA proteins in auxin signaling transduction.
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