ReviewDeutsches Arzteblatt international2019
Cognitive Deficits Following Intensive Care.
Review in Deutsches Arzteblatt international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Non-pharmacological interventions to support the cognitive rehabilitation of patients admitted to the intensive care unit: An umbrella review.Nursing in critical care · 2025Pooled it
- Longitudinal Cognitive Recovery After Critical Illness: Trajectories in Sepsis and Non-Sepsis Survivors.Journal of intensive care medicine · 2026Article
- Rethinking Mechanical Ventilation: Can Ventilation Mode Influence Long-Term Cognitive Outcomes in ICU Patients with COVID-19?Journal of clinical medicine · 2026Article
- Trajectories of post-discharge cognitive function and associated risk factors in ICU survivors: a secondary analysis.Scientific reports · 2025Article
- Longitudinal Cognitive Recovery in Survivors of Critical Illness: Impact of Sepsis and Benzodiazepine Exposure.medRxiv : the preprint server for health sciences · 2025Article
- Codesign of a Quality Improvement Tool for Adults With Prolonged Critical Illness: A Modified Delphi Consensus Study.Critical care explorations · 2024Article
- Long term cognitive dysfunction among critical care survivors: associated factors and quality of life-a multicenter cohort study.Annals of intensive care · 2024Article
- Induced Coma, Death, and Organ Transplantation: A Physiologic, Genetic, and Theological Perspective.International journal of molecular sciences · 2023Review
- Brain functional connectivity alterations associated with neuropsychological performance 6-9 months following SARS-CoV-2 infection.Human brain mapping · 2023Article
- Disentangling the cognitive, physical, and mental health sequelae of COVID-19.Cell reports. Medicine · 2022Article
- Neuropsychological functioning in post-ICU patients after severe COVID-19 infection: The role of cognitive reserve.Brain, behavior, & immunity - health · 2022Article
- Psychiatric management of Patients in intensive care units.Indian journal of psychiatry · 2022Article
- Post-intensive Care Syndrome.Annals of geriatric medicine and research · 2021Article
- Host-Microbiome Interactions Mediated by Phenolic Metabolites in Chronically Critically Ill Patients.Metabolites · 2021Article
- Prolonged anesthesia alters brain synaptic architecture.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Updated guidance on the management of COVID-19: from an American Thoracic Society/European Respiratory Society coordinated International Task Force (29 July 2020).European respiratory review : an official journal of the European Respiratory Society · 2020Review
- Vitamin B1 Deficiency Should not be Forgotten.Deutsches Arzteblatt international · 2020Article
- In Reply.Deutsches Arzteblatt international · 2020Article
- Positive Experiences With Piracetam.Deutsches Arzteblatt international · 2020Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIllnesses that necessitate intensive care can impair cognitive function severely over the long term, leaving patients less able to cope with the demands of everyday living and markedly lowering their quality of life. There has not yet been any comprehensive study of the cognitive sequelae of critical illness among non- surgical patients treated in intensive care. The purpose of this review is to present the available study findings on cognitive deficits in such patients, with particular at- tention to prevalence, types of deficit, clinical course, risk factors, prevention, and treatment.
methodsThis review is based on pertinent publications retrieved by a selective search in MEDLINE.
resultsThe literature search yielded 3360 hits, among which there were 14 studies that met our inclusion criteria. 17-78% of patients had cognitive deficits after dis- charge from the intensive care unit; most had never had a cognitive deficit before. Cognitive impairment often persisted for up to several years after discharge (0.5 to 9 years) and tended to improve over time. The only definite risk factor is delirium.
conclusionCognitive dysfunction is a common sequela of the treatment of non-surgical patients in intensive care units. It is a serious problem for the affected persons and an increasingly important socio-economic problem as well. The effective management of delirium is very important. General conclusions are hard to draw from the available data because of heterogeneous study designs, varying methods of measurement, and differences among patient cohorts. Further studies are needed so that study designs and clinical testing procedures can be standard- ized and effective measures for prevention and treatment can be identified.
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