Evidence map›Paper›PMID 31617429›Full record

ArticleThe Journal of international medical research2020

Association of

Shengli Wang, Shuguang Zuo, Zhigang Liu, Xinying Ji, Zhenqiang Yao, Xinchun Wang

Abstract read
In one paragraph

Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Association ofFrontiers in medicine · 2025
    Article
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  11. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shengli WangDepartment of Orthopedics,the First Affiliated Hospital of Henan University, Kaifeng, Henan, China.
Shuguang ZuoMolecular Biology Laboratory,Huaihe Hospital of Henan University,Kaifeng, Henan,China.
Zhigang LiuDepartment of Orthopedics,the First Affiliated Hospital of Henan University, Kaifeng, Henan, China.
Xinying JiMolecular Immunology Laboratory,Basic Medical College of Henan University, Kaifeng,Henan, China.
Zhenqiang YaoMolecular Biology Laboratory,the First Affiliated Hospital of Henan University, Kaifeng,Henan, China.
Xinchun WangMolecular Biology Laboratory,the First Affiliated Hospital of Henan University, Kaifeng,Henan, China.ORCID https://orcid.org/0000-0001-7880-6328

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective was to explore the association of methylene tetrahydrofolate reductase (

methodsTwo hundred ninety-six patients with RA were enrolled (cases) and 120 healthy individuals served as controls. The genotypes of

resultsWe detected no significant differences in

conclusionsIn Chinese Han patients with RA, the

Indexed as

Antirheumatic AgentsArthritis, RheumatoidChinaGenotypeHumansMethotrexateMethylenetetrahydrofolate Reductase (NADPH2)Polymorphism, Single NucleotideAntirheumatic AgentsMethotrexateMethylenetetrahydrofolate Reductase (NADPH2)MTHFR protein, humanefficacymethotrexateMTHFRpolymorphismRFC-1Rheumatoid arthritistoxicity

Identifiers

PMID31617429
PMCPMC7607194

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.