Evidence map›Paper›PMID 31617342›Full record

ReviewACS infectious diseases2020

Signaling Natural Products from Human Pathogenic Bacteria.

Zhijuan Hu, Wenjun Zhang

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in ACS infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. TargetingRSC medicinal chemistry · 2023
    Review
  5. Article
  6. Small molecule natural products in human nasal/oral microbiota.Journal of industrial microbiology & biotechnology · 2021
    Review
  7. Adaptations ofFrontiers in microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Zhijuan HuDepartment of Chemical and Biomolecular Engineering , University of California Berkeley , 201 Gilman Hall , Berkeley , California 94720 , United States.
Wenjun ZhangDepartment of Chemical and Biomolecular Engineering , University of California Berkeley , 201 Gilman Hall , Berkeley , California 94720 , United States.ORCID 0000-0001-9348-972X
Chan Zuckerberg Initiative (United States) · USUniversity of California, Berkeley · US

Funding

In Situ Natural Product Labeling and ApplicationsDP2AT009148 · NCCIH · UNIVERSITY OF CALIFORNIA BERKELEY · PI ZHANG, WENJUN · 2015 to 2020
$2.8M
NCCIH NIH HHS DP2 AT009148
6 · The paper itself

Abstract

Natural products from microorganisms are important small molecules that play roles in various biological processes like cellular growth, motility, nutrient acquisition, stress response, biofilm formation, and defense. It is hypothesized that pathogens exploit these molecules to regulate virulence and persistence during infections. Here, we present selected examples of signaling natural products from human pathogenic bacteria that use these metabolites to gain a competitive advantage. Targeting these signaling systems provides novel strategies to antimicrobial treatments.

Indexed as

Host Microbial InteractionsSignal TransductionAnimalsAnti-Bacterial AgentsBacteriaBiological ProductsHumansSecondary MetabolismVirulenceAnti-Bacterial AgentsBiological Productsnonribosomal peptidespathogenesispolyketidessecondary metabolitessiderophorestherapeutic targetsvirulence

Identifiers

PMID31617342
PMCPMC7609248
OpenAlexW2981097993

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.