Evidence map›Paper›PMID 31617217›Full record

ArticleBioethics2020

Drawing the line on in vitro gametogenesis.

Lauren Notini, Christopher Gyngell, Julian Savulescu

Abstract read
In one paragraph

Article in Bioethics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Solones, Solo Reproduction and Vice.Asian bioethics review · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. In vitro gametogenesis (IVG): reflections from a workshop.Journal of assisted reproduction and genetics · 2024
    Article
  9. Synthetic Embryo Models: A New Frontier in Assisted Reproduction?Reproductive sciences (Thousand Oaks, Calif.) · 2024
    Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lauren NotiniMelbourne Law School, University of Melbourne, Carlton, Victoria, Australia.ORCID 0000-0001-5055-9505
Christopher GyngellBiomedical Ethics Research Group, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Julian SavulescuBiomedical Ethics Research Group, Murdoch Children's Research Institute, Parkville, Victoria, Australia.ORCID 0000-0003-1691-6403

Funding

Wellcome Trust WT203132/Z/16/Z
6 · The paper itself

Abstract

In vitro gametogenesis (IVG) might offer numerous research and clinical benefits. Some potential clinical applications of IVG, such as allowing opposite-sex couples experiencing infertility to have genetically related children, have attracted support. Others, such as enabling same-sex reproduction and solo reproduction, have attracted significantly more criticism. In this paper, we examine how different ethical principles might help us to draw lines and distinguish between ethically desirable and undesirable uses of IVG. We discuss the alleged distinction between therapeutic and non-therapeutic uses of assisted reproduction in the context of IVG, and show how it is both problematic to apply in practice and theoretically dubious. We then discuss how the ethical principles of reproductive justice and beneficence apply to IVG for opposite-sex reproduction, same-sex reproduction, and solo reproduction. We suggest that these principles generate strong reasons for the use of IVG for opposite-sex and same-sex reproduction, but not for solo reproduction.

Indexed as

Ethical AnalysisGametogenesisParentsPrinciple-Based EthicsBeneficenceFamilyFemaleHarm ReductionHealth Services AccessibilityHumansIn Vitro TechniquesMaleReproductive RightsReproductive Techniques, AssistedRiskassisted reproductive technologybioethicsin vitro-derived gametesin vitro gametogenesisresource allocationsame-sex reproduction

Identifiers

PMID31617217
PMCPMC6973109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.