ArticleObesity surgery2020
Thyroid Homeostasis After Bariatric Surgery in Obese Cases.
Article in Obesity surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Time Trends in Thyroid Hormone Changes Following Bariatric Surgery: A Systematic Review and Meta-Analysis.Obesity surgery · 2026Pooled it
- Thyroid function post-bariatric surgery: an updated systematic review and meta-analysis.Obesity surgery · 2025Pooled it
- Hormonal adaptations to weight loss: Responses to an oral glucose load 4 weeks after obesity surgery and low-energy diet.Diabetes, obesity & metabolism · 2025Trial
- Different impact of sleeve gastrectomy and Roux-en-Y gastric bypass on thyroid function and levothyroxine requirements.Eating and weight disorders : EWD · 2026Observational
- Does Bariatric Surgery Impact Hypothyroidism and Vice Versa? Results of a Prospective Comparative Study.Obesity surgery · 2025Article
- Thyroid Volume Stabilization and Nodule Progression After Bariatric Surgery: Insights from a Retrospective Study.Obesity surgery · 2025Article
- Review
- Effect of Laparoscopic Sleeve Gastrectomy on Hypothyroidism in Patients with Morbid Obesity: A one-year follow-up Prospective Cohort Study.Iranian journal of pathology · 2025Article
- Impaired sensitivity to thyroid hormones is associated with ASCVD risk factors in Beijing in euthyroid population: a cross-sectional study.Frontiers in endocrinology · 2025Article
- Total weight loss induces the alteration in thyroid function after bariatric surgery.Frontiers in endocrinology · 2024Article
- Insight of the Biopharmaceutical Implication of Sleeve Gastrectomy on Levothyroxine Absorption in Hypothyroidism Patients.Obesity surgery · 2024Article
- Gastric bypass surgery in morbid obesity: Influence on thyroid function tests and insulin resistance status.Caspian journal of internal medicine · 2024Article
- Alterations in gastric and gut microbiota following sleeve gastrectomy in high-fat diet-induced obese rats.Scientific reports · 2023Article
- Thyroid-stimulating hormone may participate in insulin resistance by activating toll-like receptor 4 in liver tissues of subclinical hypothyroid rats.Molecular biology reports · 2023Article
- Impact of Bariatric Surgery on Thyroid Morphology and Thyroid Function.Obesity surgery · 2023Article
- Thyroid Function Before and After Laparoscopic Sleeve Gastrectomy in Patients with Obesity.Obesity surgery · 2022Article
- Long-term Effect of Bariatric Surgery on the Use of Levothyroxine and Thyroid Levels.Obesity surgery · 2022Observational
- Thyroid Function Alteration in Obesity and the Effect of Bariatric Surgery.Journal of clinical medicine · 2022Review
- Relationship of Vitamin A and Thyroid Function in Individuals With Obesity and After Laparoscopic Sleeve Gastrectomy.Frontiers in nutrition · 2022Article
- Oral drug dosing following bariatric surgery: General concepts and specific dosing advice.British journal of clinical pharmacology · 2021Review
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to determine changes in thyroid hormones and morphology with weight loss after bariatric surgery in obese patients.
methodsThis prospective study was performed in our endocrinology and surgery clinic. Pre- and post-bariatric surgery thyroid function tests and thyroid ultrasonography parameters were compared.
resultsFour hundred seventy-two patients were included in the study. Mean weight loss after surgery was 30.7 ± 5.1 kg. TSH levels decreased statistically significantly parallel with weight loss and decreased BMI (p = 0.025) after bariatric surgery. However, no statistically significant change was observed in fT4 or fT3 levels (p > 0.05). A significant increase in thyroid parenchyma echogenicity, correlated with weight loss and time elapsed since surgery, was detected at ultrasonography (US) grayscale histogram analysis compared with muscle echogenicity (p = 0.032). An increase in echogenicity was even detected in patients with isoechoic thyroid parenchyma before surgery. Fasting insulin and HOMA-IR levels decreased after surgery (p = 0.010 and p = 0.001, respectively). Patients were divided into three groups based on weight loss. In group 3, preoperative TSH of 4.1 ± 0.7 decreased to 1.6 ± 0.7 postoperatively (p = 0.001), while preoperative HOMA-IR of 4.9 ± 1.9 decreased to 2.4 ± 0.8 postoperatively (p = 0.001).
conclusionsObesity causes thyroid hormone resistance through a mechanism similar to insulin resistance and leads to an increase in TSH similar to hyperinsulinemia. Our findings show that echogenicity at thyroid US increases in line with weight loss following bariatric surgery.
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