Evidence map›Paper›PMID 31616859›Full record

ArticleJournal of the Canadian Association of Gastroenterology2019

Anxiety, Depression and Quality of Life Improve After One Month and Three Months of Home Parenteral Nutrition: A Pilot Study in a Canadian Population.

Maria Ines Pinto-Sanchez, Shannon Gadowsky, Suzan McKenzie, Michael J Raphael, Anne Childs, Marroon Thabane, Suzanne Hansen, John K Marshall, David Armstrong

Abstract read
In one paragraph

Article in Journal of the Canadian Association of Gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Observational
  3. Quality of care of oncological patients with home parenteral nutrition.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Observational
  4. Safety and quality of parenteral nutrition: Areas for improvement and future perspectives.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2024
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maria Ines Pinto-SanchezDivision of Gastroenterology & Farncombe Family Digestive Heath Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-9040-9824
Shannon GadowskyDivision of Gastroenterology & Farncombe Family Digestive Heath Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Suzan McKenzieDivision of Gastroenterology & Farncombe Family Digestive Heath Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Michael J RaphaelDivision of Medical Oncology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Anne ChildsDivision of Gastroenterology & Farncombe Family Digestive Heath Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Marroon ThabaneDivision of Gastroenterology & Farncombe Family Digestive Heath Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Suzanne HansenDivision of Gastroenterology & Farncombe Family Digestive Heath Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
John K MarshallDivision of Gastroenterology & Farncombe Family Digestive Heath Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
David ArmstrongDivision of Gastroenterology & Farncombe Family Digestive Heath Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0003-2487-1479

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients receiving home parenteral nutrition (HPN) have a reduced quality of life (QoL), but it is unknown if this is associated with psychiatric comorbidities such as anxiety or depression.

aimThe aim of this study was to assess anxiety, depression and QoL in patients transitioning from hospital to HPN.

methodsWe conducted a prospective study in adult patients receiving parenteral nutrition (PN) during transition from hospital to home. We assessed anxiety and depression (Hospital Anxiety and Depression Scale; HADS), health-related quality of life (HRQoL; SF-36) and health status (EQ-5D) before discharge and again later at one and three months after HPN was started.

resultsOf the 29 patients, 15 had an underlying malignancy. At baseline, 93% of patients with malignancy had anxiety or depression (HADS A and/or HADS D >7) or both, while of the patients without malignancy, 60% had anxiety, and 40% had depression. Questionnaires were completed by 21 patients at one month and by 15 at three months. Anxiety and depression scores decreased significantly after one month of HPN (mean difference [MD] anxiety: 4.3; 95% CI, 1.2-7.5,

conclusionHome parenteral nutrition is associated with improvements in anxiety, depression and HRQoL at one month and three months after discharge from hospital. The improvements in Qol, anxiety and depression seem greater in patients with underlying malignancy.

Indexed as

Home PNMalignancyParenteral nutritionQuality of life

Identifiers

PMID31616859
PMCPMC6785684

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.