ArticleFrontiers in immunology2019
Clustering of Activated CD8 T Cells Around Malaria-Infected Hepatocytes Is Rapid and Is Driven by Antigen-Specific Cells.
Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Liver sinusoid constraints make random search of CD8 T cells for Plasmodium parasites efficient.bioRxiv : the preprint server for biology · 2025Article
- Heterogeneity in killing efficacy of individual effector CD8Proceedings. Biological sciences · 2023Article
- Article
- Mathematical Modeling to Guide Experimental Design: T Cell Clustering as a Case Study.Bulletin of mathematical biology · 2022Article
- Liver Environment-Imposed Constraints Diversify Movement Strategies of Liver-Localized CD8 T Cells.Journal of immunology (Baltimore, Md. : 1950) · 2022Article
- Chemoprophylaxis vaccination with a Plasmodium liver stage autophagy mutant affords enhanced and long-lasting protection.NPJ vaccines · 2021Article
- Lessons Learned for Pathogenesis, Immunology, and Disease of Erythrocytic Parasites:Frontiers in cellular and infection microbiology · 2021Review
- Article
- A New Method Based on the von Mises-Fisher Distribution Shows that a Minority of Liver-Localized CD8 T Cells Display Hard-To-Detect Attraction toFrontiers in bioinformatics · 2021Article
- Application of Brunauer-Emmett-Teller (BET) theory and the Guggenheim-Anderson-de Boer (GAB) equation for concentration-dependent, non-saturable cell-cell interaction dose-responses.Journal of pharmacokinetics and pharmacodynamics · 2020Article
- A Peptide-Based PD1 Antagonist Enhances T-Cell Priming and Efficacy of a Prophylactic Malaria Vaccine and Promotes Survival in a Lethal Malaria Model.Frontiers in immunology · 2020Article
- Clustering of Activated CD8 T Cells Around Malaria-Infected Hepatocytes Is Rapid and Is Driven by Antigen-Specific Cells.Frontiers in immunology · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Malaria, a disease caused by parasites of the Plasmodium genus, begins when Plasmodium-infected mosquitoes inject malaria sporozoites while searching for blood. Sporozoites migrate from the skin via blood to the liver, infect hepatocytes, and form liver stages which in mice 48 h later escape into blood and cause clinical malaria. Vaccine-induced activated or memory CD8 T cells are capable of locating and eliminating all liver stages in 48 h, thus preventing the blood-stage disease. However, the rules of how CD8 T cells are able to locate all liver stages within a relatively short time period remains poorly understood. We recently reported formation of clusters consisting of variable numbers of activated CD8 T cells around
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