Evidence map›Paper›PMID 31616406›Full record

ArticleFrontiers in immunology2019

Identification and Characterization of Post-activated B Cells in Systemic Autoimmune Diseases.

Sarah Y Weißenberg, Franziska Szelinski, Eva Schrezenmeier, Ana-Luisa Stefanski, Annika Wiedemann, Hector Rincon-Arevalo, Anna Welle, Annemarie Jungmann, Karl Nordström, Jörn Walter and 9 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 63 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Identification and Validation of Hub Genes in Hidradenitis Suppurativa.Clinical, cosmetic and investigational dermatology · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. SHP2: its association and roles in systemic lupus erythematosus.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 4 countries.

Sarah Y WeißenbergDepartment of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany.
Franziska SzelinskiDepartment of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany.
Eva SchrezenmeierDepartment of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany.
Ana-Luisa StefanskiDepartment of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany.
Annika WiedemannDepartment of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany.
Hector Rincon-ArevaloDepartment of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany.
Anna WelleDepartment of Genetics and Epigenetics, Saarland University, Saarbrücken, Germany.
Annemarie JungmannDepartment of Genetics and Epigenetics, Saarland University, Saarbrücken, Germany.
Karl NordströmDepartment of Genetics and Epigenetics, Saarland University, Saarbrücken, Germany.
Jörn WalterDepartment of Genetics and Epigenetics, Saarland University, Saarbrücken, Germany.
Juliana Imgenberg-KreuzDepartment of Medical Sciences, Rheumatology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Gunnel NordmarkDepartment of Medical Sciences, Rheumatology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Lars RönnblomDepartment of Medical Sciences, Rheumatology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Prathyusha BachaliRILITE Research Institute, Charlottesville, VA, United States.
Michelle D CatalinaRILITE Research Institute, Charlottesville, VA, United States.
Amrie C GrammerRILITE Research Institute, Charlottesville, VA, United States.
Peter E LipskyRILITE Research Institute, Charlottesville, VA, United States.
Andreia C LinoDepartment of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany.
Thomas DörnerDepartment of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany.
Ampel BioSolutions (United States) · USCharité - Universitätsmedizin Berlin · DESaarland University · DEGerman Rheumatism Research Centre · DEScience for Life Laboratory · SEUniversidad de Antioquia · COUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune diseases (AID) such as systemic lupus erythematosus (SLE), primary Sjögren's syndrome (pSS), and rheumatoid arthritis (RA) are chronic inflammatory diseases in which abnormalities of B cell function play a central role. Although it is widely accepted that autoimmune B cells are hyperactive

Indexed as

Agammaglobulinaemia Tyrosine KinaseAutoimmune DiseasesB-LymphocytesHumansProtein Tyrosine PhosphatasesReceptors, Antigen, B-CellSyk KinaseAgammaglobulinaemia Tyrosine KinaseProtein Tyrosine PhosphatasesReceptors, Antigen, B-CellSyk KinaseanergyB cell receptor signalingCD40post-activationprimary Sjögren's syndromerheumatoid arthritissystemic lupus erythematosustoll-like receptor 9

Identifiers

PMID31616406
PMCPMC6768969
OpenAlexW2970617452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.