ArticleFrontiers in immunology2019
Docosahexaenoic Acid Suppresses Silica-Induced Inflammasome Activation and IL-1 Cytokine Release by Interfering With Priming Signal.
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Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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0cells of the map it votes in
20citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
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Who cites it
20 citing papers in PubMed, 30 citations in OpenAlex.
- Docosahexaenoic Acid (DHA) Decreases IL-6 and Prostaglandin-Endoperoxide Synthase 2 mRNA Expression and IL-6 Protein Release, While Increasing Resolvin D1 and CXCL8 mRNA Expression and Protein Release in BovineEndometrial Cells.Animals : an open access journal from MDPI · 2025Article
- Omega-3 fatty acid synergy with glucocorticoid in mouse lupus macrophage model: targeting pathogenic pathways to reduce steroid dependence.Frontiers in immunology · 2025Article
- ω-3PUFAs Inhibit Hypoxia-Induced Retinal Neovascularization via Regulating Microglial Pyroptosis through METTL14-Mediated m6A Modification of IFNB1 mRNA.Applied biochemistry and biotechnology · 2024Article
- Dietary docosahexaenoic acid supplementation inhibits acute pulmonary transcriptional and autoantibody responses to a single crystalline silica exposure in lupus-prone mice.Frontiers in immunology · 2024Article
- Lysosomal BK channels facilitate silica-induced inflammation in macrophages.Inhalation toxicology · 2024Article
- Lipidome modulation by dietary omega-3 polyunsaturated fatty acid supplementation or selective soluble epoxide hydrolase inhibition suppresses rough LPS-accelerated glomerulonephritis in lupus-prone mice.Frontiers in immunology · 2023Article
- Crystalline silica-induced proinflammatory eicosanoid storm in novel alveolar macrophage model quelled by docosahexaenoic acid supplementation.Frontiers in immunology · 2023Article
- A Lipid Perspective on Regulated Pyroptosis.International journal of biological sciences · 2023Review
- β-caryophyllene and docosahexaenoic acid, isolated or associated, have potential antinociceptive and anti-inflammatory effects in vitro and in vivo.Scientific reports · 2022Article
- Dietary Postbiotics Reduce Cytotoxicity and Inflammation Induced by Crystalline Silica in an In Vitro RAW 264.7 Macrophage Model.Foods (Basel, Switzerland) · 2022Article
- Fetal Liver-Derived Alveolar-like Macrophages: A Self-Replicating Ex Vivo Model of Alveolar Macrophages for Functional Genetic Studies.ImmunoHorizons · 2022Article
- Single cell analysis of docosahexaenoic acid suppression of sequential LPS-induced proinflammatory and interferon-regulated gene expression in the macrophage.Frontiers in immunology · 2022Article
- Dietary Fatty Acid Regulation of the NLRP3 Inflammasome via the TLR4/NF-Oxidative medicine and cellular longevity · 2022Article
- The Mechanism and Effect of Autophagy, Apoptosis, and Pyroptosis on the Progression of Silicosis.International journal of molecular sciences · 2021Review
- Nutritional Factors in Occupational Lung Disease.Current allergy and asthma reports · 2021Review
- Docosahexaenoic acid impacts macrophage phenotype subsets and phagolysosomal membrane permeability with particle exposure.Journal of toxicology and environmental health. Part A · 2021Article
- Long Chain Fatty Acids as Modulators of Immune Cells Function: Contribution of FFA1 and FFA4 Receptors.Frontiers in physiology · 2021Review
- Requisite Omega-3 HUFA Biomarker Thresholds for Preventing Murine Lupus Flaring.Frontiers in immunology · 2020Article
- Omega-3 Docosahexaenoic Acid (DHA) Impedes Silica-Induced Macrophage Corpse Accumulation by Attenuating Cell Death and Potentiating Efferocytosis.Frontiers in immunology · 2020Article
- Resolution of Pulmonary Inflammation Induced by Carbon Nanotubes and Fullerenes in Mice: Role of Macrophage Polarization.Frontiers in immunology · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Kathryn A WierengaDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, United States.
Josephine WeeDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States.
Kristen N GilleyDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States.
Lichchavi D RajasingheDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States.
Melissa A BatesInstitute for Integrative Toxicology, Michigan State University, East Lansing, MI, United States.
Mikhail A GavrilinDivision of Pulmonary, Critical Care and Sleep Medicine, Ohio State University, Columbus, OH, United States.
Andrij HolianDepartment of Biomedical and Pharmaceutical Sciences, Center for Environmental Health Sciences, University of Montana, Missoula, MT, United States.
James J PestkaInstitute for Integrative Toxicology, Michigan State University, East Lansing, MI, United States.
Michigan State University · USCenter for Environmental Health · USThe Ohio State University · US
Funding
MULTIDISCIPLINARY TRAINING IN ENVIRONMENTAL TOXICOLOGYT32ES007255 · NIEHS · MICHIGAN STATE UNIVERSITY · PI JOHN J LAPRES · 1989 to 2026
$9.3MRole of alveolar macrophage in omega-3 fatty acid amelioration of silica-triggered autoimmunity.R01ES027353 · NIEHS · MICHIGAN STATE UNIVERSITY · PI Andrew Olive · 2017 to 2026
$4.8MOmega-3 Fatty Acid Suppression of Silica-induced Inflammasome Activation in a Novel Alveolar Macrophage ModelF31ES030593 · NIEHS · MICHIGAN STATE UNIVERSITY · PI WIERENGA, KATHRYN ALEXANDRIA · 2019 to 2021
$90kNIEHS NIH HHS F31 ES030593NIEHS NIH HHS R01 ES027353NIEHS NIH HHS T32 ES007255USDA 1020129
Abstract
Occupational exposure to respirable crystalline silica (cSiO
Indexed as
AnimalsCell LineDocosahexaenoic AcidsHEK293 CellsHumansInflammasomesInflammationInterleukin-1LungMacrophagesMiceMice, Inbred C57BLNigericinRAW 264.7 CellsSilicon DioxideDocosahexaenoic AcidsInflammasomesInterleukin-1NigericinSilicon Dioxidecell deathinflammasomein vitromacrophageomega-3 fatty acidssilica
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.