Evidence map›Paper›PMID 31616396›Full record

ArticleFrontiers in microbiology2019

SCFAs-Induced GLP-1 Secretion Links the Regulation of Gut Microbiome on Hepatic Lipogenesis in Chickens.

Jian-Mei Zhang, Yin-Shuang Sun, Li-Qin Zhao, Tian-Tian Chen, Mei-Na Fan, Hong-Chao Jiao, Jing-Peng Zhao, Xiao-Juan Wang, Fu-Chang Li, Hai-Fang Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.

  1. Low Weight Loss Response to Incretin Analogs: A Systematic Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. GLP-1 agonists and the gut microbiome: A bidirectional relationship.British journal of clinical pharmacology · 2026
    Review
  11. [Research progress in mechanisms of dietary resistant starch for regulating glucose and lipid metabolism].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Review
  12. Nutrients · 2026
    Review
  13. Article
  14. Molecular Mechanisms and Antidiabetic Effects of Mango (International journal of molecular sciences · 2025
    Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Gut neuropeptide involvement in Parkinson's disease.American journal of physiology. Gastrointestinal and liver physiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jian-Mei ZhangShandong Provincial Key Laboratory of Animal Biotechnology and Disease Control, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an, China.
Yin-Shuang SunShandong Key Laboratory of Animal Microecological Agents, Biological Research Institute, Shandong Baolai-Leelai Bioengineering Co., Ltd., Tai'an, China.
Li-Qin ZhaoCollege of Life Sciences, Shandong Agricultural University, Tai'an, China.
Tian-Tian ChenShandong Key Laboratory of Animal Microecological Agents, Biological Research Institute, Shandong Baolai-Leelai Bioengineering Co., Ltd., Tai'an, China.
Mei-Na FanShandong Key Laboratory of Animal Microecological Agents, Biological Research Institute, Shandong Baolai-Leelai Bioengineering Co., Ltd., Tai'an, China.
Hong-Chao JiaoShandong Provincial Key Laboratory of Animal Biotechnology and Disease Control, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an, China.
Jing-Peng ZhaoShandong Provincial Key Laboratory of Animal Biotechnology and Disease Control, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an, China.
Xiao-Juan WangShandong Provincial Key Laboratory of Animal Biotechnology and Disease Control, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an, China.
Fu-Chang LiShandong Provincial Key Laboratory of Animal Biotechnology and Disease Control, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an, China.
Hai-Fang LiCollege of Life Sciences, Shandong Agricultural University, Tai'an, China.
Hai LinShandong Provincial Key Laboratory of Animal Biotechnology and Disease Control, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an, China.
Shandong Agricultural University · CNYebio Bioengineering (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of gut microbiota and its metabolites on fat metabolism have been widely reported in human and animals. However, the critical mediators and the signal transductions are not well demonstrated. As ovipara, chicken represents a specific case in lipid metabolism that liver is the main site of lipid synthesis. The aim of this study is to elucidate the linkage of gut microbiota and fat synthesis in broiler chickens. The broilers were subjected to dietary treatments of combined probiotics (

Indexed as

AMPK/ACCchickenGLP-1gut microbiotahepatic lipogenesisMAPKSCFAs

Identifiers

PMID31616396
PMCPMC6775471
OpenAlexW2971914322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.