ReviewFrontiers in psychology2019
Neuropsychological Findings in Gulf War Illness: A Review.
Review in Frontiers in psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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Who cites it
34 citing papers in PubMed.
- Safety, Tolerability and Efficacy of Dietary Supplementation with Concord Grape Juice in Gulf War Veterans with Gulf War Illness: A Phase I/IIA, Randomized, Double-Blind, Placebo-Controlled Trial.International journal of environmental research and public health · 2020Trial
- The comparative ameliorating effects of an amorphous formula of curcumin and α-glycosyl isoquercitrin on hippocampal dysfunction in a rat gulf war illness model.Metabolic brain disease · 2026Article
- Polycyclic aromatic hydrocarbon exposure in battlefield and beyond: Implications for environmental- and human health.Toxicology reports · 2026Review
- Gulf War Illness: Neurological Impacts, Pathophysiological Insights, and Therapeutic Prospects.Molecular neurobiology · 2026Review
- A Supplemental Women's Health Questionnaire for Women Veterans With Military Environmental Exposures: Project Development and Implementation.JMIR formative research · 2025Article
- Association of deployment characteristics and exposures with persistent ill health among 1990-1991 Gulf War veterans in the VA Million Veteran Program.Environmental health : a global access science source · 2024Article
- Comprehensive examination of resting state fMRI connectomics yields new insights into brain function deficits in Gulf War illness after accounting for heterogeneity in brain impairment across the ill veteran population.Neuroimage. Reports · 2024Article
- Review
- Olfactory and cognitive decrements in 1991 Gulf War veterans with gulf war illness/chronic multisymptom illness.Environmental health : a global access science source · 2024Article
- Cognitive decrements in 1991 Gulf War veterans: associations with Gulf War illness and neurotoxicant exposures in the Boston Biorepository, Recruitment, and Integrative Network (BBRAIN) cohorts.Environmental health : a global access science source · 2023Article
- Genetic association between the APOE ε4 allele, toxicant exposures and Gulf war illness diagnosis.Environmental health : a global access science source · 2023Article
- Fingolimod mitigates memory loss in a mouse model of Gulf War Illness amid decreasing the activation of microglia, protein kinase R, and NFκB.Neurotoxicology · 2023Article
- Pathophysiological basis and promise of experimental therapies for Gulf War Illness, a chronic neuropsychiatric syndrome in veterans.Psychopharmacology · 2023Review
- The prevalence of mild cognitive impairment in Gulf War veterans: a follow-up study.Frontiers in neuroscience · 2023Article
- Long-Term Anxiety-like Behavior and Microbiota Changes Induced in Mice by Sublethal Doses of Acute Sarin Surrogate Exposure.Biomedicines · 2022Article
- Evaluation of a Gene-Environment Interaction ofEnvironmental health perspectives · 2022Article
- Health symptom trajectories and neurotoxicant exposures in Gulf War veterans: the Ft. Devens cohort.Environmental health : a global access science source · 2022Article
- Veteran-derived cerebral organoids display multifaceted pathological defects in studies on Gulf War Illness.Frontiers in cellular neuroscience · 2022Article
- A review of chemical warfare agents linked to respiratory and neurological effects experienced in Gulf War Illness.Inhalation toxicology · 2022Review
- Association of the tissue microstructural diffusivity and translocator protein PET in Gulf War Illness.Brain, behavior, & immunity - health · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review paper summarizes the accumulation of research investigating neuropsychological outcomes in veterans with Gulf War illness (GWI). Earlier research focused on Gulf War veterans (GW) who were deployed versus non-deployed, as well as those who were symptomatic versus asymptomatic, or compared neuropsychological test results to published norms. Further research became more sophisticated, investigating specific GWI criteria, as well as the result of neurotoxicant exposure and the relationship to possible neurocognitive outcomes. As the early research supported both psychological and physiological effects on GWI; current research as summarized in this literature review supports the presence of neuropsychological deficits, particularly in the domains of attention, executive functioning, memory, and motor functioning related to chemical exposures that can be exacerbated by comorbid mood-related conditions. The same test battery has not been used consistently making it difficult to compare results among studies. Therefore, researchers created a resource to provide recommendations for the recently listed Neuropsychological Tests for Common Data Elements (CDEs) for use in all future GWI studies. Future research is necessary to further understand patterns of neuropsychological test data and how these decrements may relate to immunological or other biological markers, and the impact of trauma from physical and psychological stressors. In conclusion, there is consistent evidence that GWI is characterized by neuropsychological decrements - with future research these findings may aid in the diagnosis and assessment of treatment trial efficacy of GW veterans.
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