ArticleScientific reports2019
A Low-Power CMOS Microfluidic Pump Based on Travelling-Wave Electroosmosis for Diluted Serum Pumping.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- CMOS Electrokinetic Systems and Fabrication Approaches for On-CMOS 3D Electrodes.Electrophoresis · 2026Review
- A One-Step-Packaged CMOS/Microfluidics Wireless Bio-Analyzer for Point-of-Care Diagnostics.IEEE journal of solid-state circuits · 2025Article
- A passive flow microreactor for urine creatinine test.Microsystems & nanoengineering · 2025Article
- Microfluidic-based electrically driven particle manipulation techniques for biomedical applications.RSC advances · 2025Review
- Active-matrix digital microfluidics design for field programmable high-throughput digitalized liquid handling.iScience · 2024Article
- Integrating Microfluidics and Electronics in Point-of-Care Diagnostics: Current and Future Challenges.Micromachines · 2022Review
- Review
- A Hybrid Microfluidic Electronic Sensing Platform for Life Science Applications.Micromachines · 2022Article
- Integrated Magnetohydrodynamic Pump with Magnetic Composite Substrate and Laser-Induced Graphene Electrodes.Polymers · 2021Article
- A practical microfluidic pump enabled by acoustofluidics and 3D printing.Microfluidics and nanofluidics · 2021Article
- Small-volume point-of-care analytical methods.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microfluidic pump is an essential component in lab-on-chip applications. It is of importance to develop an active microfluidic pump with low-power and low-cost characteristics for portable and miniaturized diagnostic systems. Taking advantages of CMOS technologies, in this work, we report a low-power microfluidic pump based on travelling-wave electroosmosis (TWEO). Utilizing an integrated driving circuit, this monolithic CMOS microfluidic pump can be operated at 1.5 V driving voltage with a power consumption of 1.74 mW. The integrated driving circuit consist of a resistor-capacitor (RC) oscillator, a 90-degrees phase-shift square wave generator, and buffer amplifiers. Moreover, capabilities of the developed CMOS TWEO pump to drive diluted human serum are characterized. The flow rate of diluted human serum with dilution ratio of 1:1000 can achieve 51 μm/s. This is the first time demonstrating an in-situ CMOS-based microfluidic pump to drive the clinical diluted serum sample. As a consequence, this work demonstrates an essential component of CMOS biotechnologies for potential applications of portable in vitro diagnosis (IVD) systems.
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Registered trials
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