Evidence map›Paper›PMID 31616013›Full record

ArticleScientific reports2019

Glutathione deficiency induces epigenetic alterations of vitamin D metabolism genes in the livers of high-fat diet-fed obese mice.

Rajesh Parsanathan, Sushil K Jain

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 70 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Uncovering hidden vitamin D deficiency in overweight children.World journal of clinical pediatrics · 2025
    Review
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  6. Article
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  8. Article
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  10. Article
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  18. Vitamin D and COVID-19: where are we now?Postgraduate medicine · 2023
    Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rajesh ParsanathanDepartment of Pediatrics and Center for Cardiovascular Diseases and Sciences, Louisiana State University Health Sciences Center-Shreveport, 1501 Kings Highway, Shreveport, LA, 71130, USA.ORCID http://orcid.org/0000-0001-8973-3507
Sushil K JainDepartment of Pediatrics and Center for Cardiovascular Diseases and Sciences, Louisiana State University Health Sciences Center-Shreveport, 1501 Kings Highway, Shreveport, LA, 71130, USA. sjain@lsuhsc.edu.ORCID http://orcid.org/0000-0002-9574-0436
Louisiana State University Health Sciences Center Shreveport · US

Funding

L-cysteine, PIP3 and Insulin Signaling in DiabetesR01AT007442 · NCCIH · LOUISIANA STATE UNIV HSC SHREVEPORT · PI JAIN, SUSHIL K · 2014 to 2015
$643k
NCCIH NIH HHS R01 AT007442
6 · The paper itself

Abstract

Obesity has been correlating with low levels of glutathione (GSH) and 25-hydroxyvitamin D3 (25(OH)VD

Indexed as

Epigenesis, GeneticAnimalsBiosynthetic PathwaysCalcifediolDiet, High-FatDisease Models, AnimalDNA MethylationDown-RegulationGlutathioneHumansLiverMaleMiceMice, ObeseObesityVitamin D DeficiencyCalcifediolGlutathione

Identifiers

PMID31616013
PMCPMC6794254
OpenAlexW2980541831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.