Evidence map›Paper›PMID 31615957›Full record

ArticlemBio2019

Antibiotics and Host-Tailored Probiotics Similarly Modulate Effects on the Developing Avian Microbiome, Mycobiome, and Host Gene Expression.

Tonya L Ward, Bonnie P Weber, Kristelle M Mendoza, Jessica L Danzeisen, Katharine Llop, Kevin Lang, Jonathan B Clayton, Elicia Grace, Jeanine Brannon, Igor Radovic and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
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  14. A Novel ProbioticMicrobiology spectrum · 2022
    Article
  15. Article
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  17. Article
  18. Article
  19. Modulatory Effects ofAnimals : an open access journal from MDPI · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 1 country.

Tonya L WardDepartment of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, Minnesota, USA.
Bonnie P WeberDepartment of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, Minnesota, USA.
Kristelle M MendozaDepartment of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, Minnesota, USA.
Jessica L DanzeisenDepartment of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, Minnesota, USA.
Katharine LlopDepartment of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, Minnesota, USA.
Kevin LangDepartment of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, Minnesota, USA.
Jonathan B ClaytonDepartment of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, Minnesota, USA.
Elicia GraceDepartment of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, Minnesota, USA.
Jeanine BrannonDepartment of Animal Science, University of Minnesota, Saint Paul, Minnesota, USA.
Igor RadovicDepartment of Animal Science, University of Minnesota, Saint Paul, Minnesota, USA.
Mai BeauclaireDepartment of Computer Science and Engineering, University of Minnesota, Minneapolis, Minnesota, USA.
Timothy J HeiselDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Dan KnightsDepartment of Computer Science and Engineering, University of Minnesota, Minneapolis, Minnesota, USA.
Carol CardonaDepartment of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, Minnesota, USA.
Mike KogutAgricultural Research Service, United States Department of Agriculture, College Station, Texas, USA.
Casey JohnsonDepartment of Animal and Food Sciences, University of Delaware, Newark, Delaware, USA.
Sally L NollDepartment of Animal Science, University of Minnesota, Saint Paul, Minnesota, USA.
Ryan ArsenaultDepartment of Animal and Food Sciences, University of Delaware, Newark, Delaware, USA.ORCID 0000-0002-4534-278X
Kent M ReedDepartment of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, Minnesota, USA.
Timothy J JohnsonDepartment of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, Minnesota, USA tjj@umn.edu.
University of Minnesota · USUniversity of Delaware · USAgricultural Research Service · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The microbiome is important to all animals, including poultry, playing a critical role in health and performance. Low-dose antibiotics have historically been used to modulate food production animals and their microbiome. Identifying alternatives to antibiotics conferring similar modulatory properties has been elusive. The purpose of this study was to determine if a host-tailored probiotic could recapitulate effects of a low-dose antibiotic on host response and the developing microbiome. Over 13 days of life, turkey poults were supplemented continuously with a low-dose antibiotic or oral supplementation of a prebiotic with or without two different probiotics (8 cage units,

Indexed as

ProbioticsAnimalsAnti-Bacterial AgentsMicrobiotaMycobiomeRNA, Ribosomal, 16STurkeysAnti-Bacterial AgentsRNA, Ribosomal, 16Santibioticbacteriafungihostmicrobiotapoultryprobiotics

Identifiers

PMID31615957
PMCPMC6794479
OpenAlexW2981073453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.