Evidence map›Paper›PMID 31615956›Full record

ArticlemBio2019

Distinct Requirements for Tail-Anchored Membrane Protein Biogenesis in Escherichia coli.

Markus Peschke, Mélanie Le Goff, Gregory M Koningstein, Norbert O Vischer, Abbi Abdel-Rehim, Stephen High, Peter van Ulsen, Joen Luirink

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Markus PeschkeThe Amsterdam Institute of Molecules, Medicines and Systems, VU University Amsterdam, Amsterdam, The Netherlands.
Mélanie Le GoffThe Amsterdam Institute of Molecules, Medicines and Systems, VU University Amsterdam, Amsterdam, The Netherlands.
Gregory M KoningsteinThe Amsterdam Institute of Molecules, Medicines and Systems, VU University Amsterdam, Amsterdam, The Netherlands.
Norbert O VischerSwammerdam Institute for Life Sciences, Department of Bacterial Cell Biology and Physiology, University of Amsterdam, Amsterdam, The Netherlands.
Abbi Abdel-RehimDivision of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Stephen HighDivision of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Peter van UlsenThe Amsterdam Institute of Molecules, Medicines and Systems, VU University Amsterdam, Amsterdam, The Netherlands.
Joen LuirinkThe Amsterdam Institute of Molecules, Medicines and Systems, VU University Amsterdam, Amsterdam, The Netherlands s.luirink@vu.nl.
Vrije Universiteit Amsterdam · NLUniversity of Manchester · GBUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tail-anchored membrane proteins (TAMPs) are a distinct subset of inner membrane proteins (IMPs) characterized by a single C-terminal transmembrane domain (TMD) that is responsible for both targeting and anchoring. Little is known about the routing of TAMPs in bacteria. Here, we have investigated the role of TMD hydrophobicity in tail-anchor function in

Indexed as

Escherichia coliEscherichia coli ProteinsHydrophobic and Hydrophilic InteractionsMembrane ProteinsProtein BindingEscherichia coli Proteinsinner membrane protein, E coliMembrane ProteinsEscherichia colihydrophobicitymembrane proteinsmembrane targetingtail-anchored

Identifiers

PMID31615956
PMCPMC6794478
OpenAlexW2981204899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.