Evidence map›Paper›PMID 31615895›Full record

ArticleThe Journal of biological chemistry2019

Staphylopine and pseudopaline dehydrogenase from bacterial pathogens catalyze reversible reactions and produce stereospecific metallophores.

Jeffrey S McFarlane, Jian Zhang, Sanshan Wang, Xiaoguang Lei, Graham R Moran, Audrey L Lamb

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jeffrey S McFarlaneDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66045.ORCID 0000-0002-0033-4129
Jian ZhangBeijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Department of Chemical Biology, College of Chemistry and Molecular Engineering, and Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.
Sanshan WangBeijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Department of Chemical Biology, College of Chemistry and Molecular Engineering, and Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.
Xiaoguang LeiBeijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Department of Chemical Biology, College of Chemistry and Molecular Engineering, and Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.
Graham R MoranDepartment of Chemistry and Biochemistry, Loyola University, Chicago, Illinois 60660.
Audrey L LambDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66045 lamb@ku.edu.ORCID 0000-0002-2352-2130
Peking University · CNUniversity of Kansas · USLoyola University Chicago · US

Funding

Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Douglas E Wright · 2012 to 2026
$63.0M
X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
TRAINING GRANT IN DYNAMIC ASPECTS OF CHEMICAL BIOLOGYT32GM008545 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI LAMB, AUDREY L · 1994 to 2019
$4.9M
Novel and essential metallophores from multidrug resistant bacterial pathogensR01GM127655 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI LAMB, AUDREY L · 2018 to 2020
$910k
NIGMS NIH HHS P20 GM103418NIGMS NIH HHS P41 GM103393NIGMS NIH HHS R01 GM127655NIGMS NIH HHS T32 GM008545
6 · The paper itself

Abstract

Pseudopaline and staphylopine are opine metallophores biosynthesized by

Indexed as

BiocatalysisFluorescenceHydrolysisImidazolesIonsKetoglutaric AcidsKineticsMetalsModels, MolecularOligopeptidesOxidoreductasesPseudomonas aeruginosaStaphylococcus aureusStereoisomerismImidazolesIonsKetoglutaric AcidsMetalsOligopeptidesOxidoreductasespseudopalinestaphylopinecrystal structuredehydrogenasekineticsmetallophoreopinePseudomonas aeruginosa (P. aeruginosa)pseudopalinesiderophoreStaphylococcus aureus (S. aureus)staphylopine

Identifiers

PMID31615895
PMCPMC6879343
OpenAlexW2981219914

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.