Evidence map›Paper›PMID 31615794›Full record

SynthesisBMJ open2019

Association between soft drinks consumption and asthma: a systematic review and meta-analysis.

Abdulmohsen Hamdan Al-Zalabani, Ibrahim Noor Elahi, Abdullah Katib, Abdulmajeed G Alamri, Abdulrahman Halawani, Nasser M Alsindi, Mohammed Almatrafi, Anke Wesselius, Kelly F J Stewart

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Article
  8. Review
  9. Foundations of Pediatric Lifestyle Medicine.Children (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Association between asthma and sugar-sweetened beverage consumption in the United States pediatric population.The Journal of asthma : official journal of the Association for the Care of Asthma · 2022
    Article
  18. Article
  19. Analysis of the Relationship between Asthma and Coffee/Green Tea/Soda Intake.International journal of environmental research and public health · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abdulmohsen Hamdan Al-ZalabaniDepartment of Family and Community Medicine, Taibah University, Madinah, Saudi Arabia aalzalabani@gmail.com.ORCID 0000-0002-4937-6100
Ibrahim Noor ElahiDepartment of Family and Community Medicine, Taibah University, Joint Program of Community Medicine, Madinah, Saudi Arabia.
Abdullah KatibDepartment of Family and Community Medicine, Taibah University, Joint Program of Community Medicine, Madinah, Saudi Arabia.
Abdulmajeed G AlamriDepartment of Family and Community Medicine, Taibah University, Joint Program of Community Medicine, Madinah, Saudi Arabia.
Abdulrahman HalawaniDepartment of Family and Community Medicine, Taibah University, Joint Program of Community Medicine, Madinah, Saudi Arabia.
Nasser M AlsindiDepartment of Family and Community Medicine, Taibah University, Joint Program of Community Medicine, Madinah, Saudi Arabia.
Mohammed AlmatrafiDepartment of Family and Community Medicine, Taibah University, Joint Program of Community Medicine, Madinah, Saudi Arabia.
Anke WesseliusNUTRIM, Maastricht University, Maastricht, The Netherlands.
Kelly F J StewartNUTRIM, Maastricht University, Maastricht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo carry out meta-analysis and systematic review on the association between soft drinks consumption and asthma prevalence among adults and children.

designSystematic review and meta-analysis of observational research. DATA SOURCES: Medline, Scopus, ISI Web of Science and the Cochrane Library were searched up to December 2018. ELIGIBILITY CRITERIA: We included observational studies investigating the association between soft drinks consumption (including maternal consumption during pregnancy) and asthma or wheeze. DATA EXTRACTION AND SYNTHESIS: Data were extracted by one author and reviewed independently by two other authors. The most adjusted estimate from each original study was used in the meta-analysis. Meta-analysis was conducted using random-effects model. The quality of studies was assessed using the Newcastle-Ottawa scale and heterogeneity was evaluated using I

resultsOf 725 publications originally identified, 19 were included in this systematic review, including 3 cohort studies and 16 cross-sectional studies. Ten articles reported on children up to 18 years, 5 articles on adults (>18 years) and 2 articles on prenatal exposure. In total, 468 836 participants were included, with more than 50 000 asthma cases. Soft drinks consumption was associated with significantly increased odds of asthma in both adults (OR=1.37; 95% CI, 1.23 to 1.52) and children (OR=1.14; 95% CI, 1.06 to 1.21). Prenatal exposure had marginally statistically significant association (OR=1.11; 95% CI, 1.00 to 1.23) with asthma in children. In subgroup analysis for childhood exposure, the association persists for sugar-sweetened soft drinks but not for carbonated drinks.

conclusionOur findings show a positive association between soft drinks consumption and asthma prevalence, mostly from cross-sectional studies. Therefore, more longitudinal research is required to establish causality.

Indexed as

AdultAsthmaCarbonated BeveragesChildFemaleHumansPregnancyRisk FactorsSugar-Sweetened BeveragesSweetening AgentsSweetening Agentsasthmacarbonated beveragesepidemiologynutrition & dieteticspublic health

Identifiers

PMID31615794
PMCPMC6797295

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.