Evidence map›Paper›PMID 31615768›Full record

ArticleBiology open2019

CLASP promotes microtubule bundling in metaphase spindle independently of Ase1/PRC1 in fission yeast.

Hirohisa Ebina, Liang Ji, Masamitsu Sato

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Fission yeast Ase1Molecular biology research communications · 2021
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hirohisa EbinaLaboratory of Cytoskeletal Logistics, Department of Life Science and Medical Bioscience, Graduate School of Advanced Science and Engineering Waseda Research Institute for Science and Engineering, Waseda University, TWIns, 2-2 Wakamatsucho, Shinjuku-ku, Tokyo 162-8480, Japan.
Liang JiLaboratory of Cytoskeletal Logistics, Department of Life Science and Medical Bioscience, Graduate School of Advanced Science and Engineering Waseda Research Institute for Science and Engineering, Waseda University, TWIns, 2-2 Wakamatsucho, Shinjuku-ku, Tokyo 162-8480, Japan.ORCID http://orcid.org/0000-0003-1069-5697
Masamitsu SatoLaboratory of Cytoskeletal Logistics, Department of Life Science and Medical Bioscience, Graduate School of Advanced Science and Engineering Waseda Research Institute for Science and Engineering, Waseda University, TWIns, 2-2 Wakamatsucho, Shinjuku-ku, Tokyo 162-8480, Japan masasato@waseda.jp.ORCID http://orcid.org/0000-0001-7974-4157

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microtubules in the mitotic spindle are organised by microtubule-associated proteins. In the late stage of mitosis, spindle microtubules are robustly organised through bundling by the antiparallel microtubule bundler Ase1/PRC1. In early mitosis, however, it is not well characterised as to whether spindle microtubules are actively bundled, as Ase1 does not particularly localise to the spindle at that stage. Here we show that the conserved microtubule-associated protein CLASP (fission yeast Peg1/Cls1) facilitates bundling of spindle microtubules in early mitosis. The

Indexed as

CLASPMicrotubuleMicrotubule-associated proteinMitotic spindle

Identifiers

PMID31615768
PMCPMC6826280

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.