Evidence map›Paper›PMID 31615562›Full record

ReviewCancer imaging : the official publication of the International Cancer Imaging Society2019

Neurosurgical applications of MRI guided laser interstitial thermal therapy (LITT).

Usama Salem, Vinodh A Kumar, John E Madewell, Donald F Schomer, Dhiego Chaves de Almeida Bastos, Pascal O Zinn, Jeffrey S Weinberg, Ganesh Rao, Sujit S Prabhu, Rivka R Colen

Abstract readReview
In one paragraph

Review in Cancer imaging : the official publication of the International Cancer Imaging Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. A systematic review of ongoing clinical trials in optic pathway gliomas.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020
    Pooled it
  4. Article
  5. Article
  6. Laser interstitial thermal therapy in pediatric neurosurgery: a prospective nationwide study on indications, safety, and early outcomes.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Laser interstitial thermal therapy for the ablation of pediatric low-grade glioma: a single-institution series of 13 patients.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Fn14-Targeted Gold Nanorods for Augmenting Laser Thermal Therapy for High-Grade Gliomas.Langmuir : the ACS journal of surfaces and colloids · 2025
    Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Usama SalemDepartment of Radiology, The University of Texas Medical Branch at Galveston, Galveston, TX, 77555, USA. ussalem@utmb.edu.
Vinodh A KumarDepartment of Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
John E MadewellDepartment of Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Donald F SchomerDepartment of Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Dhiego Chaves de Almeida BastosDepartment of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Pascal O ZinnDepartment of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA, 15232, USA.
Jeffrey S WeinbergDepartment of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Ganesh RaoDepartment of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Sujit S PrabhuDepartment of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Rivka R ColenDepartment of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA, 15232, USA. colenrr@upmc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MRI-guided laser interstitial thermal therapy (LITT) is the selective ablation of a lesion or a tissue using heat emitted from a laser device. LITT is considered a less invasive technique compared to open surgery that provides a nonsurgical solution for patients who cannot tolerate surgery. Although laser ablation has been used to treat brain lesions for decades, recent advances in MRI have improved lesion targeting and enabled real-time accurate monitoring of the thermal ablation process. These advances have led to a plethora of research involving the technique, safety, and potential applications of LITT.LITT is a minimally invasive treatment modality that shows promising results and is associated with decreased morbidity. It has various applications, such as treatment of glioma, brain metastases, radiation necrosis, and epilepsy. It can provide a safer alternative treatment option for patients in whom the lesion is not accessible by surgery, who are not surgical candidates, or in whom other standard treatment options have failed. Our aim is to review the current literature on LITT and provide a descriptive review of the technique, imaging findings, and clinical applications for neurosurgery.

Indexed as

Brain NeoplasmsGliomaHumansLaser TherapyMagnetic Resonance ImagingNeuronavigationLaser ablationLaser interstitial thermal therapy

Identifiers

PMID31615562
PMCPMC6792239

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.