ArticleJournal of the Royal Society, Interface2019
Sustained scleral stiffening in rats after a single genipin treatment.
Article in Journal of the Royal Society, Interface, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 33 citations in OpenAlex.
- Biomechanical Modification of the Sclera: An Ex Vivo Study on Porcine Eyes.Investigative ophthalmology & visual science · 2026Article
- Microindentation reveals softening of the equatorial and anterior sclera during early myopia development in tree shrew eyes.Acta biomaterialia · 2025Article
- Effects of Genipin Crosslinking of Porcine Perilimbal Sclera on Mechanical Properties and Intraocular Pressure.Bioengineering (Basel, Switzerland) · 2024Article
- Computational modelling of scleral photocrosslinking: from rat to minipig to human.Journal of the Royal Society, Interface · 2024Article
- A Pilot Study to Evaluate Genipin inInternational journal of molecular sciences · 2023Article
- Morphometric Analysis of Retinal Ganglion Cell Axons in Normal and Glaucomatous Brown Norway Rats Optic Nerves.Translational vision science & technology · 2023Article
- Regional differences of the sclera in the ocular hypertensive rat model induced by circumlimbal suture.Eye and vision (London, England) · 2023Article
- Remodeling of the Lamina Cribrosa: Mechanisms and Potential Therapeutic Approaches for Glaucoma.International journal of molecular sciences · 2022Review
- Scleral crosslinking using genipin can compromise retinal structure and function in tree shrews.Experimental eye research · 2022Article
- Evaluation of Spatially Targeted Scleral Stiffening on Neuroprotection in a Rat Model of Glaucoma.Translational vision science & technology · 2022Article
- Corrigendum to "Using retinal function to define ischemic exclusion criteria for animal models of glaucoma" [Exp. Eye. Res. 202 (2021) 108354 doi: 10.1016/j.exer.2020.108354 Epub 2020 Nov 7].Experimental eye research · 2021Article
- Genipin in an Ex Vivo Corneal Model of Bacterial and Fungal Keratitis.Translational vision science & technology · 2021Article
- Genipin Delays Corneal Stromal Enzymatic Digestion.Translational vision science & technology · 2021Article
- Effect of Scleral Crosslinking Using Multiple Doses of Genipin on Experimental Progressive Myopia in Tree Shrews.Translational vision science & technology · 2021Article
- Transpupillary collagen photocrosslinking for targeted modulation of ocular biomechanics.Biomaterials · 2021Article
- Article
- Assessment of Visual and Retinal Function Following In Vivo Genipin-Induced Scleral Crosslinking.Translational vision science & technology · 2020Article
- Factors affecting optic nerve head biomechanics in a rat model of glaucoma.Journal of the Royal Society, Interface · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Scleral stiffening has been proposed as a therapy for glaucoma and myopia. Previous
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.