Evidence map›Paper›PMID 31615131›Full record

ReviewViruses2019

Pre-Transplantation Assessment of BK Virus Serostatus: Significance, Current Methods, and Obstacles.

Fatima Dakroub, Antoine Touzé, Haidar Akl, Etienne Brochot

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Consensus Definitions of BK Polyomavirus Nephropathy in Renal Transplant Recipients for Clinical Trials.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Fatima DakroubAgents infectieux, résistance et chimiothérapie Research Unit, EA 4294, Jules Verne University of Picardie, 80000 Amiens, France. fatimadakroub20@gmail.com.
Antoine TouzéInfectiologie et santé publique "Biologie des infections à polyomavirus" team, UMR INRA 1282, University of Tours, 37082 Tours, France. antoine.touze@univ-tours.fr.
Haidar AklLaboratory of Cancer Biology and Molecular Immunology, Faculty of Sciences-I, Lebanese University, Hadath 21219, Lebanon. haidar.akl@ul.edu.lb.
Etienne BrochotAgents infectieux, résistance et chimiothérapie Research Unit, EA 4294, Jules Verne University of Picardie, 80000 Amiens, France. etienne.brochot@u-picardie.fr.
Lebanese University · LBAgents infectieux, résistance et chimiothérapie · FRUniversité de Tours · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immunosuppression required for graft tolerance in kidney transplant patients can trigger latent BK polyomavirus (BKPyV) reactivation, and the infection can progress to nephropathy and graft rejection. It has been suggested that pre-transplantation BKPyV serostatus in donors and recipients is a predictive marker for post-transplantation BKPyV replication. The fact that research laboratories have used many different assay techniques to determine BKPyV serostatus complicates these data analysis. Even studies based on the same technique differed in their standard controls choice, the antigenic structure type used for detection, and the cut-off for seropositivity. Here, we review the different BKPyV VP1 antigens types used for detection and consider the various BKPyV serostatus assay techniques' advantages and disadvantages. Lastly, we highlight the obstacles in the implementation of a consensual BKPyV serologic assay in clinics (e.g., the guidelines absence in this field).

Indexed as

Kidney TransplantationBK VirusDNA, ViralGraft RejectionHumansImmunosuppression TherapyRetrospective StudiesSerologic TestsTransplant RecipientsTumor Virus InfectionsViremiaDNA, ViralBK virusBK virus serologykidney transplantationserological technique

Identifiers

PMID31615131
PMCPMC6833059
OpenAlexW2979768040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.