Evidence map›Paper›PMID 31615112›Full record

ReviewPharmaceutics2019

Recent Advances in Nanovaccines Using Biomimetic Immunomodulatory Materials.

Veena Vijayan, Adityanarayan Mohapatra, Saji Uthaman, In-Kyu Park

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 112 citations in OpenAlex.

  1. Review
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  6. Application of nanomedicines in tumor immunotherapy.Journal of molecular cell biology · 2025
    Review
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  20. Biomimetic cell membrane-coated poly(lactic-Bioengineering & translational medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Veena VijayanDepartment of Biomedical Sciences, Chonnam National University Medical School, Gwangju 58128, Korea. veenavj4392@gmail.com.
Adityanarayan MohapatraDepartment of Biomedical Sciences, Chonnam National University Medical School, Gwangju 58128, Korea. mkaditya55@gmail.com.
Saji UthamanDepartment of Polymer Science and Engineering, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Korea. sajiuthaman@gmail.com.
In-Kyu ParkDepartment of Biomedical Sciences, Chonnam National University Medical School, Gwangju 58128, Korea. pik96@jnu.ac.kr.
Chonnam National University · KRChungnam National University · KR

Funding

National Research Foundation of Korea 2014M3C1A3053035, NRF-2017M3A9F5030940 and NRF-2017M3A9E2056374, 2018R1A5A2024181 and NRF-2019M3E5D1A02068082
6 · The paper itself

Abstract

The development of vaccines plays a vital role in the effective control of several fatal diseases. However, effective prophylactic and therapeutic vaccines have yet to be developed for completely curing deadly diseases, such as cancer, malaria, HIV, and serious microbial infections. Thus, suitable vaccine candidates need to be designed to elicit appropriate immune responses. Nanotechnology has been found to play a unique role in the design of vaccines, providing them with enhanced specificity and potency. Nano-scaled materials, such as virus-like particles, liposomes, polymeric nanoparticles (NPs), and protein NPs, have received considerable attention over the past decade as potential carriers for the delivery of vaccine antigens and adjuvants, due to their beneficial advantages, like improved antigen stability, targeted delivery, and long-time release, for which antigens/adjuvants are either encapsulated within, or decorated on, the NP surface. Flexibility in the design of nanomedicine allows for the programming of immune responses, thereby addressing the many challenges encountered in vaccine development. Biomimetic NPs have emerged as innovative natural mimicking biosystems that can be used for a wide range of biomedical applications. In this review, we discuss the recent advances in biomimetic nanovaccines, and their use in anti-bacterial therapy, anti-HIV therapy, anti-malarial therapy, anti-melittin therapy, and anti-tumor immunity.

Indexed as

adjuvantsantigen-presenting cellsantigensbiomimeticnanovaccines

Identifiers

PMID31615112
PMCPMC6835828
OpenAlexW2979330021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.