Evidence map›Paper›PMID 31614910›Full record

ArticleDiagnostics (Basel, Switzerland)2019

Ocular Surface Workup in Patients with Meibomian Gland Dysfunction Treated with Intense Regulated Pulsed Light.

Luca Vigo, Leonardo Taroni, Federico Bernabei, Marco Pellegrini, Stefano Sebastiani, Andrea Mercanti, Nicola Di Stefano, Vincenzo Scorcia, Francesco Carones, Giuseppe Giannaccare

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luca VigoCarones Ophthalmology Center, 20122 Milan, Italy. lvigo@carones.com.
Leonardo TaroniOphthalmology Unit, S.Orsola-Malpighi University Hospital, University of Bologna, 40138 Bologna, Italy. leonardo.taroni1@gmail.com.
Federico BernabeiOphthalmology Unit, S.Orsola-Malpighi University Hospital, University of Bologna, 40138 Bologna, Italy. federico.bernabei89@gmail.com.
Marco PellegriniOphthalmology Unit, S.Orsola-Malpighi University Hospital, University of Bologna, 40138 Bologna, Italy. marco.pellegrini@hotmail.it.
Stefano SebastianiOphthalmology Unit, Inferni Hospital, 47923 Rimini, Italy. stefano.sebastiani3@gmail.com.
Andrea MercantiOphthalmology Unit, Inferni Hospital, 47923 Rimini, Italy. andreamercanti.vr@gmail.com.
Nicola Di StefanoOphthalmology Unit, Inferni Hospital, 47923 Rimini, Italy. nicdist@yahoo.com.
Vincenzo ScorciaDepartment of Ophthalmology, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy. vscorcia@libero.it.ORCID 0000-0001-6826-7957
Francesco CaronesCarones Ophthalmology Center, 20122 Milan, Italy. fcarones@carones.com.ORCID 0000-0002-8597-196X
Giuseppe GiannaccareDepartment of Ophthalmology, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy. giuseppe.giannaccare@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the present study was to evaluate changes of signs and symptoms in patients with meibomian gland dysfunction (MGD) treated with intense regulated pulsed light (IRPL), and to further investigate which parameter could predict positive outcomes of the procedure. Twenty-eight patients who bilaterally received three IRPL sessions at day 1, 15, and 45 satisfied the criteria and were included in the study. Non-invasive break-up time (NIBUT), lipid layer thickness (LLT), meibography, tear osmolarity, and ocular discomfort symptoms were measured before and 30 days after the last IRPL session. Qualified or complete success was defined in the presence of an improvement of symptoms associated with an increase of NIBUT (< or ≥ 20%). After IRPL treatment, median NIBUT and LLT increased from 7.5 to 10.2 s and 2.0 to 3.0, respectively (

Indexed as

dry eye diseaseevaporative dry eyeintense pulsed lightmeibomian gland diseasenon-invasive break-up time

Identifiers

PMID31614910
PMCPMC6963914

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.