Evidence map›Paper›PMID 31614776›Full record

ArticleInternational journal of environmental research and public health2019

The Association Between Decompensated Liver Cirrhosis and Deep Neck Infection: Real-World Evidence.

Ming-Shao Tsai, Geng-He Chang, Wei-Ming Chen, Chia-Yen Liu, Meng-Hung Lin, Pey-Jium Chang, Tsung-Yu Huang, Yao-Te Tsai, Ching-Yuan Wu, Cheng-Ming Hsu and 1 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. High Risk of Peritonsillar Abscess in End-Stage Renal Disease Patients: A Nationwide Real-World Cohort Study.International journal of environmental research and public health · 2021
    Article
  7. Deep Neck Infection Risk in Patients with Sleep Apnea: Real-World Evidence.International journal of environmental research and public health · 2021
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ming-Shao TsaiDepartment of Otolaryngology-Head and Neck Surgery, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan. b87401061@cgmh.org.tw.ORCID 0000-0002-9314-5940
Geng-He ChangDepartment of Otolaryngology-Head and Neck Surgery, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan. genghechang@gmail.com.
Wei-Ming ChenDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan. b8902030@gmail.com.
Chia-Yen LiuHealth Information and Epidemiology Laboratory, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan. qchiayen@gmail.com.
Meng-Hung LinHealth Information and Epidemiology Laboratory, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan. mattlin@cgmh.org.tw.ORCID 0000-0002-8594-3360
Pey-Jium ChangGraduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan. peyjiumc@mail.cgu.edu.tw.ORCID 0000-0002-6492-0346
Tsung-Yu HuangGraduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan. r12045@cgmh.org.tw.
Yao-Te TsaiDepartment of Otolaryngology-Head and Neck Surgery, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan. yaote1215@gmail.com.
Ching-Yuan WuDepartment of Traditional Chinese Medicine, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan. smbepigwu77@gmail.com.
Cheng-Ming HsuDepartment of Otolaryngology-Head and Neck Surgery, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan. scm00031@gmail.com.ORCID 0000-0003-3792-3784
Yao-Hsu YangHealth Information and Epidemiology Laboratory, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan. r95841012@ntu.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeep neck infection (DNI) can progress to become a life-threatening complication. Liver cirrhosis, which is related to poor immune conditions, is a likely risk factor for DNI. This study investigated the risk and mortality of DNI in patients with decompensated liver cirrhosis (DLC).

methodsWe performed a nationwide cohort study using the National Health Insurance Research Database (NHIRD) in Taiwan. We included a total of 33,175 patients with DLC between 2000 and 2013, from the Catastrophic Illness Patient Database, a subsection of the NHIRD, along with 33,175 patients without cirrhosis who were matched in a 1:1 proportion for age, sex, and socioeconomic status. The occurrence of DNI was the primary study outcome. The risk, treatment, and mortalities of DNI were evaluated in the study and comparison cohorts.

resultsDLC Patients had a significantly higher incidence of DNI than noncirrhotic patients (

conclusionsThis study is the first to investigate the correlation between DLC and DNI. The study findings strongly indicate that DLC is an independent risk factor for DNI. Cirrhotic patients with DNI do not have a significantly poorer survival rate than noncirrhotic patients with DNI. Therefore, physicians should be alert to potential DNI occurrence in DLC patients. Besides this, intensive care and appropriate surgical drainage can yield similar survival outcomes in DLC-DNI and noncirrhosis-DNI patients.

Indexed as

Survival RateAdultAgedAged, 80 and overCohort StudiesFemaleHumansIncidenceInfectionsLiver CirrhosisMaleMiddle AgedNeckProportional Hazards ModelsRisk FactorsTaiwanabscesscellulitiscomorbiditieshepaticliverrisk factor

Identifiers

PMID31614776
PMCPMC6843924

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.