Evidence map›Paper›PMID 31614644›Full record

ReviewInternational journal of molecular sciences2019

The Role of MicroRNAs in Selected Forms of Glomerulonephritis.

Magdalena Nalewajska, Klaudia Gurazda, Ewa Styczyńska-Kowalska, Małgorzata Marchelek-Myśliwiec, Andrzej Pawlik, Violetta Dziedziejko

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
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  4. Short-term association of CO and NOFrontiers in public health · 2023
    Article
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  7. Article
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  16. Article
  17. Towards Precision Medicine in Systemic Lupus Erythematosus.Pharmacogenomics and personalized medicine · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Magdalena NalewajskaDepartment of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, Powstańców Wlkp 72 Str, 70-111 Szczecin, Poland. magda_nalewajska@yahoo.co.uk.ORCID 0000-0001-5254-7444
Klaudia GurazdaDepartment of Biochemistry and Medical Chemistry, Pomeranian Medical University, Powstańców Wlkp 72 Str, 70-111 Szczecin, Poland. gurazdaklaudia@gmail.com.
Ewa Styczyńska-KowalskaDepartment of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, Powstańców Wlkp 72 Str, 70-111 Szczecin, Poland. styczynskae@gmail.com.ORCID 0000-0003-2718-1959
Małgorzata Marchelek-MyśliwiecDepartment of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, Powstańców Wlkp 72 Str, 70-111 Szczecin, Poland. malgorzata.marchelek@gmail.com.
Andrzej PawlikDepartment of Physiology, Pomeranian Medical University, Powstańców Wlkp 72 Str, 70-111 Szczecin, Poland. pawand@poczta.onet.pl.ORCID 0000-0001-6557-1208
Violetta DziedziejkoDepartment of Biochemistry and Medical Chemistry, Pomeranian Medical University, Powstańców Wlkp 72 Str, 70-111 Szczecin, Poland. viola@pum.edu.pl.
Pomeranian Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glomerulonephritis (GN) represents a collection of kidney diseases characterized by inflammation within the renal glomeruli and small blood vessels. The lesions that occur in other nephron structures mainly result from the harmful effects of proteinuria. In recent years, an emphasis has been placed on gaining a better insight into the pathogenesis and pathophysiology of GN in order to facilitate diagnoses and provide efficient and targeted treatments of the disease. Owing to the advanced molecular and genetic diagnostic techniques available today, researchers have been able to elucidate that most cases of GN are determined by genetic risk factors and are associated with the abnormal functioning of the immune system (the immunologically mediated forms of GN). MicroRNAs (miRNAs) are a group of single-stranded, non-coding molecules, approximately 20 nucleotides in length, that act as regulatory factors in the post-transcriptional processes capable of regulating the expression of multiple genes. In this paper we present the available research aiming to determine effects of miRNAs on the development and progression of GN and discuss the potential role of miRNAs as new diagnostic markers and therapeutic targets.

Indexed as

Biomarkers, TumorGene Expression RegulationGene Regulatory NetworksGenetic Predisposition to DiseaseGlomerulonephritisHumansMicroRNAsBiomarkers, TumorMicroRNAschronic kidney diseasefocal segmental glomerulonephritisIgA nephropathylupus nephritismicroRNAminimal chance disease

Identifiers

PMID31614644
PMCPMC6834307
OpenAlexW2980031121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.