Evidence map›Paper›PMID 31614601›Full record

ArticleMolecules (Basel, Switzerland)2019

Design, Synthesis and Investigation of the Potential Anti-Inflammatory Activity of 7-

Yilong Zhang, Yan Zheng, Wen Shi, Yahui Guo, Tao Xu, Zeng Li, Cheng Huang, Jun Li

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yilong ZhangThe Key Laboratory of Major Autoimmune Diseases, Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China. zhangyl_ahmu@126.com.
Yan ZhengThe Key Laboratory of Major Autoimmune Diseases, Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China. 13170023235@163.com.
Wen ShiThe Key Laboratory of Major Autoimmune Diseases, Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China. shiwenahaq@163.com.
Yahui GuoThe Key Laboratory of Major Autoimmune Diseases, Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China. yahuiguo_1@163.com.
Tao XuThe Key Laboratory of Major Autoimmune Diseases, Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China. xutao@ahmu.edu.cn.
Zeng LiThe Key Laboratory of Major Autoimmune Diseases, Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China. lizeng@ahmu.edu.cn.
Cheng HuangThe Key Laboratory of Major Autoimmune Diseases, Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China. huangcheng@ahmu.edu.cn.
Jun LiThe Key Laboratory of Major Autoimmune Diseases, Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230032, China. lj@ahmu.edu.cn.
Ministry of Education of the People's Republic of China · CNAnhui Medical University · CN

Funding

Higher Education Natural Science Foundation of Anhui Province KJ2019A0233National Natural Science Foundation of China No. 81770609
6 · The paper itself

Abstract

To develop new anti-inflammatory agents, a series of 7-

Indexed as

AnimalsCelecoxibCyclooxygenase 2Gene Expression RegulationHesperidinHumansHydrophobic and Hydrophilic InteractionsIndomethacinInflammationInterleukin-1betaInterleukin-6MiceNF-kappa BNitric OxideNitric Oxide Synthase Type IISignal TransductionCelecoxibCyclooxygenase 2hesperetinHesperidinIndomethacinInterleukin-1betaInterleukin-6NF-kappa BNitric OxideNitric Oxide Synthase Type IINos2 protein, mouseTumor Necrosis Factor-alphahesperetin derivativesinflammatoryNF-κBstructure-activity relationships.synthesis

Identifiers

PMID31614601
PMCPMC6832651
OpenAlexW2979642142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.