ArticleInternational journal of molecular sciences2019
Integration of Transcriptomics and Metabolomics for Pepper (
Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
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Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.
- Physiological and Molecular Approaches for Developing Thermotolerance in Vegetable Crops: A Growth, Yield and Sustenance Perspective.Frontiers in plant science · 2022Pooled it
- Molecular mechanisms and agronomic strategies for thermotolerance in chili pepper (Capsicum annuum L.).Plant cell reports · 2026Review
- From Perception to Adaptation: A Comparative Study of Plant Regulatory Networks in Response to Heat and Waterlogging Stress.Plants (Basel, Switzerland) · 2026Review
- Identification and Expression Analysis of theBiology · 2025Article
- Physiological and transcriptomic comparisons shed light on the high-temperature stress response mechanisms of Oncidium cultivars.BMC plant biology · 2025Article
- Nucleotides enriched under heat stress recruit beneficial rhizomicrobes to protect plants from heat and root-rot stresses.Microbiome · 2025Article
- Strategies to develop climate-resilient chili peppers: transcription factor optimization through genome editing.Planta · 2025Review
- Progress in Transcriptomics and Metabolomics in Plant Responses to Abiotic Stresses.Current issues in molecular biology · 2025Review
- Genome-wide association analysis and linkage mapping decipher the genetic control of primary metabolites and quality traits in Capsicum.The Plant journal : for cell and molecular biology · 2025Article
- Metabolic Pathways and Molecular Regulatory Mechanisms of Fruit Color Change During Greening Stage of Peppers (International journal of molecular sciences · 2025Article
- Integrative analysis of transcriptome and metabolome reveal molecular mechanism of tolerance to salt stress in rice.BMC plant biology · 2025Article
- Metabolome and transcriptome analyses for explore heat stress responses and adaptation mechanisms in Rhododendron henanense subsp. lingbaoense.BMC plant biology · 2025Article
- Multi-omics analysis of non-pungent (Physiology and molecular biology of plants : an international journal of functional plant biology · 2025Article
- Article
- Analysis of full length transcriptome and resistance characteristics of Atraphaxis bracteata under drought.Scientific reports · 2025Article
- Growth regulation mechanism ofFrontiers in plant science · 2025Article
- Physiological, transcriptomic, and metabolomic analyses of the chilling stress response in two melon (Cucumis melo L.) genotypes.BMC plant biology · 2024Article
- Integrating Proteomics and Metabolomics Approaches to Elucidate the Mechanism of Responses to Combined Stress in the Bell Pepper (Plants (Basel, Switzerland) · 2024Article
- Article
- Integrated transcriptomics and metabolomics provides insights into theFrontiers in plant science · 2024Article
Corrections and comments
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Authors and funding
14 authors at 5 institutions in 2 countries.
Funding
Abstract
Heat stress (HS), caused by extremely high temperatures, is one of the most severe forms of abiotic stress in pepper. In the present study, we studied the transcriptome and metabolome of a heat-tolerant cultivar (17CL30) and a heat-sensitive cultivar (05S180) under HS. Briefly, we identified 5754 and 5756 differentially expressed genes (DEGs) in 17CL30 and 05S180, respectively. Moreover, we also identified 94 and 108 differentially accumulated metabolites (DAMs) in 17CL30 and 05S180, respectively. Interestingly, there were many common HS-responsive genes (approximately 30%) in both pepper cultivars, despite the expression patterns of these HS-responsive genes being different in both cultivars. Notably, the expression changes of the most common HS-responsive genes were typically much more significant in 17CL30, which might explain why 17CL30 was more heat tolerant. Similar results were also obtained from metabolome data, especially amino acids, organic acids, flavonoids, and sugars. The changes in numerous genes and metabolites emphasized the complex response mechanisms involved in HS in pepper. Collectively, our study suggested that the glutathione metabolic pathway played a critical role in pepper response to HS and the higher accumulation ability of related genes and metabolites might be one of the primary reasons contributing to the heat resistance.
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Registered trials
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