ArticleMolecules (Basel, Switzerland)2019
Design, Synthesis and Evaluation of New Indolylpyrimidylpiperazines for Gastrointestinal Cancer Therapy.
Aaron Tan, Maria V Babak, Gopalakrishnan Venkatesan, Clarissa Lim, Karl-Norbert Klotz, Deron Raymond Herr, Siew Lee Cheong, Stephanie Federico, Giampiero Spalluto, Wei-Yi Ong and 3 more
Open access · goldAbstract read
In one paragraphArticle in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 1 citations in OpenAlex.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
13 authors at 5 institutions in 4 countries.
Aaron TanNUS Graduate School of Integrative Sciences and Engineering, National University of Singapore, Centre for Life Sciences, #05-01, 28 Medical Drive, Singapore 117456, Singapore. aarontan@u.nus.edu.ORCID 0000-0003-1966-4467 Maria V BabakDepartment of Pharmacy, National University of Singapore, Singapore 119260, Singapore. maria.babak@nus.edu.sg.ORCID 0000-0002-2009-7837 Gopalakrishnan VenkatesanDepartment of Pharmacy, National University of Singapore, Singapore 119260, Singapore. phagove@nus.edu.sg.
Clarissa LimDepartment of Pharmacy, National University of Singapore, Singapore 119260, Singapore. scifryc@nus.edu.sg.
Karl-Norbert KlotzInstitut für Pharmakologie und Toxikologie, Universität Würzburg, 97078 Würzburg, Germany. klotz@toxi.uni-wuerzburg.de.ORCID 0000-0003-3553-3205 Deron Raymond HerrDepartment of Pharmacology, National University of Singapore, Singapore 117600, Singapore. phcdrh@nus.edu.sg.ORCID 0000-0001-5755-0896 Siew Lee CheongDepartment of Pharmaceutical Chemistry, School of Pharmacy, International Medical University, 126 Jalan Jalil Perkasa 19, Bukit Jalil, Kuala Lumpur 57000, Malaysia. CheongSiewLee@imu.edu.my.
Stephanie FedericoDipartimento di Scienze Chimiche e Farmaceutiche, Università degli Studi di Trieste, 34127 Trieste, Italy. sfederico@units.it.
Giampiero SpallutoDipartimento di Scienze Chimiche e Farmaceutiche, Università degli Studi di Trieste, 34127 Trieste, Italy. spalluto@units.it.
Wei-Yi OngDepartment of Anatomy, National University of Singapore, Singapore 119260, Singapore. antongwy@nus.edu.sg.
Yu Zong ChenDepartment of Pharmacy, National University of Singapore, Singapore 119260, Singapore. csccyz@nus.edu.sg.
Jason Siau Ee LooSchool of Pharmacy, Faculty of Health and Medical Sciences, Taylor's University, 1, Jalan Taylors, Subang Jaya, Selangor 47500, Malaysia. JasonSiauEe.Loo@taylors.edu.my.ORCID 0000-0001-6976-3282 Giorgia PastorinNUS Graduate School of Integrative Sciences and Engineering, National University of Singapore, Centre for Life Sciences, #05-01, 28 Medical Drive, Singapore 117456, Singapore. phapg@nus.edu.sg.ORCID 0000-0002-2568-0626 National University of Singapore · SGUniversity of Trieste · ITIMU University · MYTaylor's University · MYUniversity of Würzburg · DE
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Indexed as
Adenosine A2 Receptor AntagonistsAnimalsCell ProliferationCHO CellsCricetinaeCricetulusGastrointestinal NeoplasmsHumansIndolesModels, MolecularPiperazinePyrimidinonesReceptor, Adenosine A2AReceptor, Adenosine A3Structure-Activity RelationshipAdenosine A2 Receptor AntagonistsADORA3 protein, humanIndolesPiperazinePyrimidinonesReceptor, Adenosine A2AReceptor, Adenosine A3gastrointestinal cancerhA3ARindolylpyrimidylpiperazinespartial agonists
Identifiers
PMID31614517
PMCPMC6832257
OpenAlexW2980127903
What OpenQuestion holds
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LicenceCC BY
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