Evidence map›Paper›PMID 31614468›Full record

ArticleMarine drugs2019

Preparation and Properties of Minocycline-Loaded Carboxymethyl Chitosan Gel/Alginate Nonwovens Composite Wound Dressings.

Yingjun Gao, Xing Zhang, Xiangyu Jin

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yingjun GaoKey Laboratory of Textile Science and Technology of the Ministry of Education, College of Textiles, Donghua University, Shanghai 201620, China. gaoyingj@hotmail.com.
Xing ZhangKey Laboratory of Textile Science and Technology of the Ministry of Education, College of Textiles, Donghua University, Shanghai 201620, China. tulip_90@163.com.
Xiangyu JinKey Laboratory of Textile Science and Technology of the Ministry of Education, College of Textiles, Donghua University, Shanghai 201620, China. jinxy@dhu.edu.cn.ORCID 0000-0003-2163-7564
Donghua University · CN

Funding

Donghua University CUSF-DH-D-2016018
6 · The paper itself

Abstract

As derivatives from marine natural biomaterials, alginate-based and chitosan-based biomaterials are commonly used in wound dressings. Calcium alginate fiber (CAF) dressings possess excellent absorption and unique gel forming performance, but the low bioactivity limits its application in wound healing. Carboxymethyl chitosan (CM-Chit) has excellent antibacterial activity, but the gel structure with weak mechanical properties restricts its application. In this study, minocycline (Mino)/CM-Chit solution was coated on the surface of plasma treated CAF needle-punched nonwovens, and then Mino loaded CM-Chit gel/CAF nonwovens composite dressings were fabricated by EDC/NHS (1-3-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide) crosslinking. The dressings had a porous composite structure, which allowed them to quickly absorb and store a large number of wound exudates. Skin-like tensile performance allowed the dressings to provide a better healing environment. Antibacterial assay against

Indexed as

AlginatesAnti-Bacterial AgentsBandagesCell LineChitosanEscherichia coliGelsHumansMinocyclineStaphylococcus aureusWound HealingAlginatesAnti-Bacterial Agentscarboxymethyl-chitosanChitosanGelsMinocyclinealginate fibersantibacterial activitycarboxymethyl chitosandrug releasewound dressings

Identifiers

PMID31614468
PMCPMC6835814
OpenAlexW2979295192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.