ArticleAntioxidants (Basel, Switzerland)2019
Iron-Binding and Anti-Fenton Properties of Novel Amino Acid-Derived Cyclic Imide Dioximes.
Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 4 citations in OpenAlex.
- Theoretical Study of the Iron Complexes with Aminoguanidine: Investigating Secondary Antioxidant Activity.Antioxidants (Basel, Switzerland) · 2020Article
- Theoretical Study of the Iron Complexes with Lipoic and Dihydrolipoic Acids: Exploring Secondary Antioxidant Activity.Antioxidants (Basel, Switzerland) · 2020Article
- Protein Formulations Containing Polysorbates: Are Metal Chelators Needed at All?Antioxidants (Basel, Switzerland) · 2020Article
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2 authors at 1 institution in 1 country.
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Abstract
We present a novel route for the preparation of amino acid-derived cyclic imide dioxime derivatives. Readily accessible amino acids were conveniently converted to their corresponding cyclic imide dioximes in simple synthetic steps. The aim of this work was to describe and compare the iron-chelating and antioxidant properties of synthesized compounds in relation to their molecular structure, and in particular, which of those features are essential for iron(II)-chelating ability. The glutarimide dioxime moiety has been established as an iron(II)-binding motif and imparts potent anti-Fenton properties to the compounds. Compound
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