ArticleJournal of cardiovascular imaging2019
Coronary Artery Dose-Volume Parameters Predict Risk of Calcification After Radiation Therapy.
Article in Journal of cardiovascular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 39 citations in OpenAlex.
- Estimation of Detailed Cardiac Doses for Pediatric Radiation Therapy Patients in National Wilms Tumor Study.International journal of radiation oncology, biology, physics · 2026Article
- Coronary artery calcium and cardiovascular risk factors analysis after radiotherapy for breast cancer (the CLARIFIER: a gender-based preventive medicine study).Frontiers in cardiovascular medicine · 2025Article
- Article
- CARdioimaging in Lung Cancer PatiEnts Undergoing Radical RadioTherapy: CARE-RT Trial.Diagnostics (Basel, Switzerland) · 2023Article
- Role of Cardiac Biomarkers in Non-Small Cell Lung Cancer Patients.Diagnostics (Basel, Switzerland) · 2023Article
- Next Generation Risk Markers in Preventive Cardio-oncology.Current atherosclerosis reports · 2022Review
- Artificial intelligence and imaging: Opportunities in cardio-oncology.American heart journal plus : cardiology research and practice · 2022Article
- Medial Arterial Calcification: A Significant and Independent Contributor of Peripheral Artery Disease.Arteriosclerosis, thrombosis, and vascular biology · 2022Review
- Coronary artery calcium score on standard of care oncologic CT scans for the prediction of adverse cardiovascular events in patients with non-small cell lung cancer treated with concurrent chemoradiotherapy.Frontiers in cardiovascular medicine · 2022Article
- Cardiac Computed Tomography in Cardio-Oncology:JACC. CardioOncology · 2021Review
- Past, Present, and Future of Radiation-Induced Cardiotoxicity: Refinements in Targeting, Surveillance, and Risk Stratification.JACC. CardioOncology · 2021 · on this mapReview
- Application of an automatic segmentation method for evaluating cardiac structure doses received by breast radiotherapy patients.Physics and imaging in radiation oncology · 2021Article
- Cardiac Toxicity of Thoracic Radiotherapy: Existing Evidence and Future Directions.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2021Review
- Dexamethasone is Associated With a Lower Risk of the Progression of Thoracic Aortic Calcification in Breast Cancer Survivors.Frontiers in pharmacology · 2021Article
- Incidence and Onset of Severe Cardiac Events After Radiotherapy for Esophageal Cancer.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2020Article
- Review
- Emerging Challenges of Radiation-Associated Cardiovascular Dysfunction (RACVD) in Modern Radiation Oncology: Clinical Practice, Bench Investigation, and Multidisciplinary Care.Frontiers in cardiovascular medicine · 2020Review
- Potential of Calcium Scoring CT to Identify Subclinical Coronary Artery Disease in Patients with Prior Thoracic Irradiation.Journal of cardiovascular imaging · 2019Article
- Preventive Cardio-Oncology: The Time Has Come.Frontiers in cardiovascular medicine · 2019Article
Corrections and comments
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Authors and funding
20 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundRadiation exposure increases the risk of coronary artery disease (CAD). We explored the association of CAD with coronary artery dose-volume parameters in patients treated with 3D-planned radiation therapy (RT).
methodsPatients who received thoracic RT and were evaluated by cardiac computed tomography ≥ 1 year later were included. Demographic data and cardiac risk factors were retrospectively collected. Dosimetric data (mean heart dose, d
resultsTwenty patients with a median age of 53 years at the time of RT were included. Nine patients (45%) had ≥ 3/6 conventional cardiac risk factors. Patients received RT for breast cancer (10, 50%), lung cancer (6, 30%), or lymphoma/myeloma (4, 20%) with a median dose of 60 Gy. CAC scans were performed a median of 32 months after RT. CAC score was significantly associated with radiation dose and presence of diabetes. In a multivariable model adjusted for diabetes, segmental coronary artery dosimetric parameters (d
conclusionsCoronary artery radiation exposure is strongly correlated with subsequent segmental CAC score. Coronary calcification may occur soon after RT and in individuals with conventional cardiac risk factors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.