Evidence map›Paper›PMID 31614162›Full record

ReviewJournal of neuroscience methods2020

Modeling drug exposure in rodents using e-cigarettes and other electronic nicotine delivery systems.

Cristina Miliano, E Reilly Scott, Laura B Murdaugh, Emma R Gnatowski, Christine L Faunce, Megan S Anderson, Malissa M Reyes, Ann M Gregus, Matthew W Buczynski

Open access · greenAbstract readReview
In one paragraph

Review in Journal of neuroscience methods, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Modeling complex age-related eye disease.Progress in retinal and eye research · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. THC and CBD: Villain versus Hero? Insights into Adolescent Exposure.International journal of molecular sciences · 2023
    Review
  9. Article
  10. Article
  11. Exposure to Nicotine Vapor Produced by an Electronic Nicotine Delivery System Causes Short-Term Increases in Impulsive Choice in Adult Male Rats.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
    Article
  12. Review
  13. Article
  14. Female rats self-administer heroin by vapor inhalation.Pharmacology, biochemistry, and behavior · 2020
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Cristina MilianoSchool of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States.
E Reilly ScottSchool of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States.
Laura B MurdaughSchool of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States.
Emma R GnatowskiSchool of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States.
Christine L FaunceSchool of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States.
Megan S AndersonSchool of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States.
Malissa M ReyesSchool of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States.
Ann M GregusSchool of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States.
Matthew W BuczynskiSchool of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States. Electronic address: mwb@vt.edu.
Virginia Tech · US

Funding

15-LOX-1 as a druggable target in the acute to chronic pain transition of rheumatoid arthritisR01AR075241 · NIAMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI GREGUS, ANN MARIE · 2019 to 2023
$1.7M
The role of the OEA synthase NAPE-PLD in nicotine signaling and rewardR00DA035865 · NIDA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI BUCZYNSKI, MATTHEW WALLACE · 2017 to 2019
$747k
NIAMS NIH HHS R01 AR075241NIDA NIH HHS R00 DA035865
6 · The paper itself

Abstract

Smoking tobacco products is the leading cause of preventable death worldwide. Coordinated efforts have successfully reduced tobacco cigarette smoking in the United States; however, electronic cigarettes (e-cigarette) and other electronic nicotine delivery systems (ENDS) recently have replaced traditional cigarettes for many users. While the clinical risks associated with long-term ENDS use remain unclear, advancements in preclinical rodent models will enhance our understanding of their overall health effects. This review examines the peripheral and central effects of ENDS-mediated exposure to nicotine and other drugs of abuse in rodents and evaluates current techniques for implementing ENDS in preclinical research.

Indexed as

Electronic Nicotine Delivery SystemsAnimalsCentral Nervous System StimulantsDisease Models, AnimalNicotinePeripheral Nervous System AgentsRatsRodentiaVapingCentral Nervous System StimulantsNicotinePeripheral Nervous System AgentsE-cigaretteENDSMouseNicotineRatVaping

Identifiers

PMID31614162
PMCPMC7012754
OpenAlexW2979344310

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.