Evidence map›Paper›PMID 31613686›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2020

Impact of Neck Disability on Health-Related Quality of Life among Head and Neck Cancer Survivors.

Marci L Nilsen, Lingyun Lyu, Michael A Belsky, Leila J Mady, Dan P Zandberg, David A Clump, Heath D Skinner, Shyamal Das Peddada, Susan George, Jonas T Johnson

Abstract readComparative Study
In one paragraph

Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Can Manual Therapy Alter Muscle Stiffness in Patients With Spinal Accessory Nerve Injury?Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Trial
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Widespread distribution and altered pain processing in head and neck cancer survivors at long-term after treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marci L NilsenDepartment of Acute and Tertiary Care, School of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Lingyun LyuDepartment of Biostatistics, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Michael A BelskyDepartment of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Leila J MadyDepartment of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Dan P ZandbergDivision of Hematology/Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA.
David A ClumpDepartmment of Radiation Oncology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Heath D SkinnerDepartmment of Radiation Oncology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Shyamal Das PeddadaDepartment of Biostatistics, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Susan GeorgeCenters for Rehab Services, UPMC, Pittsburgh, Pennsylvania, USA.
Jonas T JohnsonDepartment of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Leonard J. Appleman · 1988 to 2026
$158.0M
WILD TYPE P53-BASED ADJUVANT IMMUNOTHERAPY FOR SCCHNP50CA097190 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Heath Devin Skinner, Jose P. Zevallos · 2004 to 2026
$49.6M
Research Training in OtolaryngologyT32DC000066 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHNSON, JONAS T. · 2003 to 2017
$1.8M
NCI NIH HHS P30 CA047904NCI NIH HHS P50 CA097190NIDCD NIH HHS T32 DC000066
6 · The paper itself

Abstract

objectiveAlthough neck impairment has been described following surgical resection, limited studies have investigated its prevalence in nonsurgical treatment. The purpose of this study is to determine the prevalence and predictors of neck disability following head and neck cancer (HNC) treatment and to explore its association with quality of life (QOL). STUDY

designCross-sectional study.

settingHNC survivorship clinic. SUBJECTS AND

methodsWe identified 214 survivors who completed treatment ≥1 year prior to evaluation in the clinic. Self-reported neck impairment was measured using the Neck Disability Index. QOL was measured using the University of Washington QOL Questionnaire, with physical and social subscale scores calculated. Regression analysis and trend tests were employed to explore associations.

resultsOver half of survivors (54.2%) reported neck disability. The odds of neck disability in survivors who received nonsurgical treatment and those who received surgery plus adjuvant treatment were 3.46 and 4.98 times higher compared to surgery alone (

conclusionThis study revealed a high prevalence of neck disability following nonsurgical treatment. While neck disability is an established sequela of surgical resection, the impact of nonsurgical treatment has gone unrecognized. Early identification and intervention to prevent progression of neck disability are crucial to optimize QOL.

Indexed as

Quality of LifeSurvivorsAcademic Medical CentersAdultAgedConfidence IntervalsConservative TreatmentCross-Sectional StudiesDatabases, FactualDisability EvaluationFemaleHead and Neck NeoplasmsHumansLinear ModelsMaleMiddle Agedhead and neck cancerneck disabilityquality of lifesurvivorship

Identifiers

PMID31613686
PMCPMC7263303

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.