ArticleAmerican journal of respiratory and critical care medicine2020
Losartan Rescues Inflammation-related Mucociliary Dysfunction in Relevant Models of Cystic Fibrosis.
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Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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32citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
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Who cites it
32 citing papers in PubMed, 43 citations in OpenAlex.
- Potassium Channels of the Airway Epithelium.Acta physiologica (Oxford, England) · 2026Review
- Oral losartan yields subtherapeutic airway exposure compared to nebulized delivery and fails to improve mucociliary clearance in cystic fibrosis.Frontiers in pharmacology · 2026Article
- Differential BK channel potentiation by vanzacaftor enantiomers enables therapy for modulator-ineligible people with cystic fibrosis.The Journal of clinical investigation · 2025Article
- Effects of Losartan, Rapamycin, Doxycycline and botulinum toxin A: an experimentally induced urethral trauma model in rats.Journal of molecular histology · 2025Article
- Therapeutic strategies to reverse cigarette smoke-induced ion channel and mucociliary dysfunction in COPD airway epithelial cells.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Development of a multi-analysis model using an epithelial-fibroblast co-culture system as an alternative to animal testing.Environmental analysis, health and toxicology · 2024Article
- Cystic fibrosis.Nature reviews. Disease primers · 2024Review
- Article
- The combination of propylene glycol and vegetable glycerin e-cigarette aerosols induces airway inflammation and mucus hyperconcentration.Scientific reports · 2024Article
- Furin as a therapeutic target in cystic fibrosis airways disease.European respiratory review : an official journal of the European Respiratory Society · 2023Review
- E-cigarette aerosols of propylene glycol impair BK channel activity and parameters of mucociliary function.American journal of physiology. Lung cellular and molecular physiology · 2023Article
- Assessment of Carbon Nanotubes on Barrier Function, Ciliary Beating Frequency and Cytokine Release in In Vitro Models of the Respiratory Tract.Nanomaterials (Basel, Switzerland) · 2023Article
- Angiotensin-(1-7) alleviates acute lung injury by activating the Mas receptor in neutrophil.Annals of translational medicine · 2022Article
- The CFTR Amplifier Nesolicaftor Rescues TGF-β1 Inhibition of Modulator-Corrected F508del CFTR Function.International journal of molecular sciences · 2022Article
- The Advances of Broad-Spectrum and Hot Anti-Coronavirus Drugs.Microorganisms · 2022Review
- Losartan ameliorates TGF-β1-induced CFTR dysfunction and improves correction by cystic fibrosis modulator therapies.The Journal of clinical investigation · 2022Article
- Animal models of cystic fibrosis in the era of highly effective modulator therapies.Current opinion in pharmacology · 2022Review
- Vegetable glycerin e-cigarette aerosols cause airway inflammation and ion channel dysfunction.Frontiers in pharmacology · 2022Article
- Revisiting the Large-Conductance Calcium-Activated Potassium (BKCa) Channels in the Pulmonary Circulation.Biomolecules · 2021Review
- Update in Pediatrics 2020.American journal of respiratory and critical care medicine · 2021Article
Corrections and comments
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Authors and funding
15 authors at 5 institutions in 1 country.
Michael D KimDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas.ORCID 0000-0003-2103-6603
Nathalie BaumlinDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas.ORCID 0000-0002-5341-6785
Makoto YoshidaDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas.
Deepika PolineniDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas.
Sebastian F SalatheDivision of Pulmonary, Critical Care and Sleep Medicine, University of Miami School of Medicine, Miami, Florida.
Joseph K DavidDivision of Pulmonary, Critical Care and Sleep Medicine, University of Miami School of Medicine, Miami, Florida.
Charles A PeloquinCollege of Pharmacy and Emerging Pathogens Institute, University of Florida, Gainesville, Florida.
Adam WannerDivision of Pulmonary, Critical Care and Sleep Medicine, University of Miami School of Medicine, Miami, Florida.
John S DennisDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas.
Juliette SaillandDivision of Pulmonary, Critical Care and Sleep Medicine, University of Miami School of Medicine, Miami, Florida.
Philip WhitneyDivision of Pulmonary, Critical Care and Sleep Medicine, University of Miami School of Medicine, Miami, Florida.
Frank T HorriganDepartment of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas; and.
Juan R SabaterMount Sinai Medical Center, Miami Beach, Florida.
William M AbrahamMount Sinai Medical Center, Miami Beach, Florida.
Matthias SalatheDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas.ORCID 0000-0001-9092-4861
University of Miami · USUniversity of Kansas Medical Center · USMount Sinai Medical Center · USBaylor College of Medicine · USUniversity of Florida · US
Funding
Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Michael M Ittmann · 2007 to 2026
$73.9MUsing Integrated Omics to Identify Dysfunctional Genetic Mechanisms Influencing Schizophrenia and Sleep DisturbancesP20GM130423 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Kalyani Pyaram, Steven Allan Soper · 2019 to 2026
$21.5MAnti-inflammatory therapy to augment CFTR rescue in CF patientsR01HL133240 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SALATHE, MATTHIAS A · 2017 to 2020
$2.7MMechanisms of mucociliary dysfunction in cystic fibrosis related diabetesR01HL157942 · NHLBI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI KIM, MICHAEL D, SALATHE, MATTHIAS A · 2021 to 2024
$2.7MDevelopment of a Novel High-Throughput Screening Platform for BK Channel ModulatoR01GM105817 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI HORRIGAN, FRANK T · 2013 to 2015
$913kNCI NIH HHS P30 CA125123NHLBI NIH HHS R01 HL133240NHLBI NIH HHS R01 HL157942NIGMS NIH HHS P20 GM130423NIGMS NIH HHS R01 GM105817
Abstract
PubMed holds no abstract for this paper.
Indexed as
Angiotensin II Type 1 Receptor BlockersAnimalsBronchiCells, CulturedCystic FibrosisDisease Models, AnimalEpithelial CellsFemaleHumansInflammationLosartanMucociliary ClearanceSheepAngiotensin II Type 1 Receptor BlockersLosartanangiotensin receptor antagonistsciliahuman neutrophil elastasemucustransforming growth factor β
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.