Evidence map›Paper›PMID 31613326›Full record

ArticleInternational health2020

Quality of antimalarials in Kinshasa peri-urban areas with regard to local pharmaceutical legislation and regulation.

Don Jethro Mavungu Landu, Michel Frédérich, Joseph Manzambi Kuwekita, Christian Bongo-Pasi Nswe, J K Mbinze, Sophie Liégeois, Nicodème Kalenda Tshilombo, Mineze Kwete Minga, Patient Ciza Hamuli, Philippe Hubert and 1 more

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Article in International health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Don Jethro Mavungu LanduLaboratory of Pharmacognosy, CIRM, Department of Pharmacy, Liège University, Liège 4000, Belgium.
Michel FrédérichLaboratory of Pharmacognosy, CIRM, Department of Pharmacy, Liège University, Liège 4000, Belgium.
Joseph Manzambi KuwekitaDepartment of Public Health Sciences, Liège University, Liège 4000, Belgium.
Christian Bongo-Pasi NsweFaculty of Public Health, Université des Sciences et des Technologies de Lodja, Sankuru 83, Democratic Republic of Congo.
J K MbinzeLaboratory of Drug Analysis, Department of Galenic Pharmacy and Drug Analysis, University of Kinshasa, Kinshasa 10, Democratic Republic of Congo.
Sophie LiégeoisLaboratory of Analytical Pharmaceutical Chemistry, CIRM, Department of Pharmacy, Liège University, Liège 4000, Belgium.
Nicodème Kalenda TshilomboLaboratory of Analytical Pharmaceutical Chemistry, CIRM, Department of Pharmacy, Liège University, Liège 4000, Belgium.
Mineze Kwete MingaAdvanced School of Translation and Interpretation, Université Pédagogique Nationale, Kinshasa 10, Democratic Republic of Congo.
Patient Ciza HamuliLaboratory of Drug Analysis, Department of Galenic Pharmacy and Drug Analysis, University of Kinshasa, Kinshasa 10, Democratic Republic of Congo.
Philippe HubertLaboratory of Analytical Pharmaceutical Chemistry, CIRM, Department of Pharmacy, Liège University, Liège 4000, Belgium.
Roland Marini Djang'eing'aLaboratory of Analytical Pharmaceutical Chemistry, CIRM, Department of Pharmacy, Liège University, Liège 4000, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the context of old pharmaceutical legislation and regulations not adapted to current realities, the aim of the present study was to evaluate the existing pharmaceutical system in peri-urban areas of Kinshasa.

methodsA prospective study was carried out during the period 2016-2018. The most used antimalarial medicines were identified through household and pharmaceutical establishment surveys. The samples of the obtained medicines were assayed with generic separation methods using the high-performance liquid chromatography technique coupled to a diode array detector. The registration status was checked for 126 antimalarial brand names. A characterization was carried out in 196 pharmaceutical establishments on the basis of standards set out by the Ministry of Health.

resultsOf the 75 samples assayed, 19% (14/75) were non-compliant. Of the 124 brand names, 46.0% (57/124) were unlicensed and 14.5% (18/124) had an expired licence. Of the 196 pharmaceutical establishments, only 2 (1.0%) had an authorization to practice, none met all the Ministry of Health minimum standards and 24.5% (48/196) met the World Health Organization Guidelines for the Storage of Essential Medicines and Other Health Commodities.

conclusionsMore resources should be mobilized to apply regulator sanctions.

Indexed as

AntimalarialsDemocratic Republic of the CongoDrug IndustryFamily CharacteristicsGovernment RegulationHumansMalariaPharmaceutical PreparationsProspective StudiesAntimalarialsPharmaceutical PreparationsCharacteristics of pharmaciesDemocratic Republic of the CongoKinshasaPeri-urban areasPharmaceutical legislation and regulationQuality of antimalarialsTesting and Treatment Algorithm

Identifiers

PMID31613326
PMCPMC7322209

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.