ArticleeLife2019
Dissection of central clock function in
Open access · goldAbstract read
In one paragraph
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 72 citations in OpenAlex.
- Article
- Circadian control of a sex-specific behavior ineLife · 2026Article
- Bidirectional regulation between circadian feeding behavior and specialized midgut clocks inbioRxiv : the preprint server for biology · 2026Article
- Stage- and tissue-specific gene editing using 4-OHT-inducible Cas9 in whole organism.The Journal of cell biology · 2026Article
- THERM-D Uncovers Distinct Neural Mechanisms Separating Morning and Evening Body Temperature Rhythms inbioRxiv : the preprint server for biology · 2026Article
- Behavioral adaptation to warm conditions via Lim1-mediated acceleration of neuronal clocks.Nature neuroscience · 2026Article
- Regulation of Metabolic Rhythms by Glial Clocks.Journal of biological rhythms · 2026Article
- Article
- A functional clock in only two dorsal clock neurons is sufficient to restore the basal circadian activity pattern ofProceedings of the National Academy of Sciences of the United States of America · 2025Article
- The cell-intrinsic circadian clock is dispensable for lateral posterior clock neuron regulation ofNeurobiology of sleep and circadian rhythms · 2025Article
- Circadian rhythms are more resilient to pacemaker neuron disruption in female Drosophila.PLoS biology · 2025Article
- Drosophila ubiquitin-specific peptidase 14 stabilizes the PERIOD protein by regulating a ubiquitin ligase SLIMB.Communications biology · 2025Article
- The circadian genes are required in DAL neurons forFrontiers in neuroscience · 2025Article
- Article
- Article
- Tissue-specific knockout in the Drosophila neuromuscular system reveals ESCRT's role in formation of synapse-derived extracellular vesicles.PLoS genetics · 2024Article
- A subclass of evening cells promotes the switch from arousal to sleep at dusk.Current biology : CB · 2024Article
- Article
- Single-cell transcriptomics reveals that glial cells integrate homeostatic and circadian processes to drive sleep-wake cycles.Nature neuroscience · 2024Article
- Dissecting neuron-specific functions of circadian genes using modified cell-specific CRISPR approaches.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Rebecca Delventhal *Department of Genetics and Development, Columbia University Medical Center, New York, United States.ORCID 0000-0002-0920-0004
Reed M O'Connor *Department of Genetics and Development, Columbia University Medical Center, New York, United States.ORCID 0000-0001-6025-772X
Meghan M Pantalia *Department of Genetics and Development, Columbia University Medical Center, New York, United States.ORCID 0000-0001-9932-4926
Matthew UlgheraitDepartment of Genetics and Development, Columbia University Medical Center, New York, United States.
Han X KimDepartment of Genetics and Development, Columbia University Medical Center, New York, United States.
Maylis K BasturkDepartment of Genetics and Development, Columbia University Medical Center, New York, United States.
Julie C CanmanDepartment of Pathology and Cell Biology, Columbia University Medical Center, New York, United States.ORCID 0000-0001-8135-2072
Mimi Shirasu-HizaDepartment of Genetics and Development, Columbia University Medical Center, New York, United States.ORCID 0000-0002-2730-1765
Columbia University Irving Medical Center · US
Funding
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007367 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI REINER, STEVEN L · 1985 to 2021
$25.1MResource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5MHormones: Molecular Mechanism of Action and FunctionsT32DK007328 · NIDDK · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI KOUSTENI, STAVROULA · 1986 to 2025
$7.8MPREDOCTORAL TRAINING GRANT IN HUMAN GENETICS &DEVELOPMET32GM007088 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI SHEN, MICHAEL M. · 1985 to 2020
$7.1MCircadian-Regulated Aging PhysiologiesR01AG045842 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Michele M Shirasu-Hiza · 2013 to 2026
$5.1MTraining in Cardiovascular Translational ResearchT32HL120826 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARKS, ANDREW ROBERT, TABAS, IRA A · 2014 to 2023
$4.7MCircadian regulation of physiological functionsR35GM127049 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Michele M Shirasu-Hiza · 2018 to 2026
$3.9MCell type-variation of cytokinesisR01GM117407 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CANMAN, JULIE C · 2016 to 2023
$2.9MCircadian regulation of phagocytosisR01GM105775 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIRASU-HIZA, MICHELE M · 2013 to 2017
$1.6MNHLBI NIH HHS T32 HL120826NIA NIH HHS R01 AG045842NIDDK NIH HHS T32 DK007328NIGMS NIH HHS R01 GM105775NIGMS NIH HHS R01 GM117407NIGMS NIH HHS R35 GM127049NIGMS NIH HHS T32 GM007088NIGMS NIH HHS T32 GM007367NIH HHS 2T32GM007367-42NIH HHS 5T32DK007328NIH HHS 5T32HL120826NIH HHS P40 OD018537NIH HHS R01GM105775NIH HHS R01GM117407NIH HHS R35GM127049
Abstract
In
Indexed as
AnimalsBrainCell CommunicationCell LineageCircadian ClocksCircadian RhythmCRISPR-Cas SystemsDarknessDrosophila melanogasterDrosophila ProteinsFeedback, PhysiologicalGene EditingGene Expression RegulationLight Signal TransductionLocomotionNerve NetDrosophila ProteinsGAL4 protein, DrosophilaNeuropeptidespdf protein, DrosophilaPeriod Circadian ProteinsPER protein, Drosophilatim protein, DrosophilaTranscription Factorscircadian rhythmCRISPR/Cas9D. melanogasterGAL4/UASgeneticsgenomicsneuroscience
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.