Evidence map›Paper›PMID 31613170›Full record

ArticleXenobiotica; the fate of foreign compounds in biological systems2020

Metabolism and disposition of 2-hydroxy-4-methoxybenzophenone, a sunscreen ingredient, in Harlan Sprague Dawley rats and B6C3F1/N mice; a species and route comparison.

Esra Mutlu, C Edwin Garner, Christopher J Wegerski, Jacob D McDonald, Barry S McIntyre, Melanie Doyle-Eisele, Suramya Waidyanatha

Open access · greenAbstract read
In one paragraph

Article in Xenobiotica; the fate of foreign compounds in biological systems, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. A Practical, Noninvasive Urine Collection Method for Mice for Large Cohort Preclinical Studies.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026
    Article
  3. Review
  4. The MAK collection for occupational health and safety · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Disposition and metabolism of ethylene glycol 2-ethylhexyl ether in Sprague Dawley rats, B6C3F1/N mice, andXenobiotica; the fate of foreign compounds in biological systems · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Esra MutluNational Institute of Environmental Health Sciences, Durham, NC, USA.
C Edwin GarnerLovelace Biomedical and Environmental Research Institute, Albuquerque, NM, USA.
Christopher J WegerskiLovelace Biomedical and Environmental Research Institute, Albuquerque, NM, USA.
Jacob D McDonaldLovelace Biomedical and Environmental Research Institute, Albuquerque, NM, USA.
Barry S McIntyreNational Institute of Environmental Health Sciences, Durham, NC, USA.
Melanie Doyle-EiseleLovelace Biomedical and Environmental Research Institute, Albuquerque, NM, USA.
Suramya WaidyanathaNational Institute of Environmental Health Sciences, Durham, NC, USA.
Mental Research Institute · USNational Institute of Environmental Health Sciences · US

Funding

Toxicological Assessments for the National Toxicology ProgramZIAES103316 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WALKER, NIGEL J · 2016 to 2019
$31.9M
Toxicological Assessments for the Division of the National Toxicology ProgramZICES103316 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WALKER, NIGEL J · 2020 to 2021
$18.5M
Intramural NIH HHS Z99 ES999999Intramural NIH HHS ZIA ES103316
6 · The paper itself

Abstract

2-Hydroxy-4-methoxybenzophenone (HMB) is a common ingredient in personal care products and used as an UV stabilizer. In these studies, disposition and metabolism of [

Indexed as

AnimalsBenzophenonesHumansMiceMice, Inbred StrainsRatsRats, Sprague-DawleySunscreening AgentsBenzophenonesoxybenzoneSunscreening Agents2-hydroxy-4-methoxybenzophenoneabsorptionbenzophenone-3distributionexcretionmetabolismoxybenzoneSunscreenUV stabilizers

Identifiers

PMID31613170
PMCPMC7166143
OpenAlexW2981007725

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.