Evidence map›Paper›PMID 31612695›Full record

ArticleTurkish journal of haematology : official journal of Turkish Society of Haematology2020

Percentages of CD4+CD8+ Double-positive T Lymphocytes in the Peripheral Blood of Adults from a Blood Bank in Bogotá, Colombia

Miguel S. Gonzalez-Mancera, Natalia I. Bolaños, Manuel Salamanca, Guillermo A. Orjuela, Ayda N. Rodriguez, John M. Gonzalez

Abstract read
In one paragraph

Article in Turkish journal of haematology : official journal of Turkish Society of Haematology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Legend or Truth: Mature CD4Biomedicines · 2023
    Review
  3. Article
  4. Double Positive CD4Cells · 2023
    Article
  5. Observational
  6. Article
  7. In Reply to: CD4+CD8+ Double-Positive T-Lymphocytes: PitfallsTurkish journal of haematology : official journal of Turkish Society of Haematology · 2020
    Article
  8. CD4+CD8+ Double-Positive T-Lymphocytes: PitfallsTurkish journal of haematology : official journal of Turkish Society of Haematology · 2020
    Article
  9. Article
  10. Double-positive T Lymphocytes Do Not Vary in Different Age Groups in Colombian Blood DonorsTurkish journal of haematology : official journal of Turkish Society of Haematology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Miguel S. Gonzalez-ManceraUniversity of los Andes, School of Medicine, Grupo de Ciencias Básicas Médicas, Bogotá, ColombiaORCID 0000-0001-7251-5984
Natalia I. BolañosUniversity of los Andes, School of Medicine, Grupo de Ciencias Básicas Médicas, Bogotá, ColombiaORCID 0000-0002-2348-6328
Manuel SalamancaUniversity of los Andes, School of Medicine, Grupo de Ciencias Básicas Médicas, Bogotá, Colombia
Guillermo A. OrjuelaNational Blood Bank, Colombian Red Cross, Bogotá, ColombiaORCID 0000-0001-8768-7092
Ayda N. RodriguezNational Blood Bank, Colombian Red Cross, Bogotá, ColombiaORCID 0000-0003-2260-465X
John M. GonzalezUniversity of los Andes, School of Medicine, Grupo de Ciencias Básicas Médicas, Bogotá, ColombiaORCID 0000-0001-6925-0620

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: CD4+CD8+ double-positive T-cells (DPTs) have been classified as a separate T-cell subpopulation, with two main phenotypes: CD4 Materials and Methods: One hundred healthy donors were enrolled in the study. Peripheral blood cells were stained for CD3, CD4, CD8, and CD154 (CD40L), and cellular viability was assessed with 7-aminoactinomycin D and analyzed by flow cytometry. Results: The median value for DPTs was 2.6% (interquartile range=1.70%-3.67%). Women had higher percentages of DPTs than men (3.3% vs. 2.1%). The subpopulation of CD4 Conclusion: DPT reference values were obtained from blood bank donors. A sex difference was found, and the CD4

Indexed as

Blood BanksBlood DonorsLymphocyte CountAdolescentAdultAgedCD4 AntigensCD8 AntigensColombiaCross-Sectional StudiesFemaleFlow CytometryHumansImmunophenotypingMaleMiddle AgedCD4 AntigensCD8 AntigensFlow cytometryLymphocyteLymphocyte subpopulationT lymphocytes

Identifiers

PMID31612695
PMCPMC7057749

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.