Evidence map›Paper›PMID 31612391›Full record

SynthesisCurrent medical science2019

Visit-to-visit Systolic Blood Pressure Variability and Stroke Risk: A Systematic Review and Meta-analysis.

Han Wang, Min Li, Shu-Hua Xie, Ye-Tong Oyang, Min Yin, Bing Bao, Zhi-Ying Chen, Xiao-Ping Yin

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Current medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pooled it
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  5. Article
  6. Blood Pressure Variability (BPV): What Clinicians Need to Know a 2025 Expert Consensus Report Endorsed by the Egyptian Society of Cardiology.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Han WangDepartment of Outpatient, The First Affiliated Hospital of Nanchang University, Nanchang, 330000, China.
Min LiDepartment of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330000, China.
Shu-Hua XieDepartment of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330000, China.
Ye-Tong OyangDepartment of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330000, China.
Min YinDepartment of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330000, China.
Bing BaoDepartment of Neurology, The Affiliated Hospital of Jiujiang University, Jiujiang, 332000, China.
Zhi-Ying ChenDepartment of Neurology, The Affiliated Hospital of Jiujiang University, Jiujiang, 332000, China. 13767263459@126.com.
Xiao-Ping YinDepartment of Neurology, The Affiliated Hospital of Jiujiang University, Jiujiang, 332000, China. xiaopingbuxiao@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visit-to-visit variability in systolic blood pressure (SBP) may have an important additional role in increasing the risk of vascular complications, including stroke. We conducted a meta-analysis to assess the relationship between visit-to-visit SBP variability (SBPV) and stroke risk. PubMed, EMBASE, and the Cochrane library databases were searched for cohort studies with data on visit-to-visit SBPV and stroke risk. Studies that reported adjusted relative risks (RRs) with 95% CIs of stroke associated with SBPV were included. Fourteen cohort studies met the inclusion criteria and were included in our meta-analysis. After adjustment for age, sex, and existing vascular risk factors, the analysis showed that the risk of stroke in patients with SBPV was significantly increased compared with patients with a small baseline SBPV [SD (RR=1.20, 95% CI=(1.07-1.35), P=0.0005), CV (RR=1.12, 95% CI=(1.00-1.26), P=0.008)]. In addition, follow-up variations of more than 5 years were associated with a higher risk of stroke than those of less than 5 years [RR=1.08, 95% CI=(1.04-1.11)]. Visit-to-visit SBPV was associated with an increased risk of stroke, especially in terms of the time of variation. Taken together, SBPV data may be useful as a preventative diagnostic method in the management of stroke.

Indexed as

Blood PressureAdultAgedAged, 80 and overCohort StudiesFemaleHumansHypertensionMaleMiddle AgedOffice VisitsRisk FactorsStrokeblood pressureblood pressure variabilitymeta-analysisstrokesystematic reviewvisit-to-visit systolic blood pressure

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.