Evidence map›Paper›PMID 31612387›Full record

SynthesisCurrent medical science2019

Tamsulosin Monotherapy Is Effective in Reducing Ureteral Stent-related Symptoms: A Meta-analysis of Randomized Controlled Studies.

Yong-Bo Chen, Liang Gao, Qing Jiang, Ke Ran, Run-Tian Luo

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Current medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Pharmacological treatment of bladder stent symptoms.Bladder (San Francisco, Calif.) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Yong-Bo Chen *Department of Urology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Liang Gao *Department of Urology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Qing JiangDepartment of Urology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. jiangqiang066@163.com.
Ke RanDepartment of Urology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Run-Tian LuoDepartment of Urology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Second Affiliated Hospital of Chongqing Medical University · CNChongqing Medical University · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the effectiveness of tamsulosin monotherapy for the treatment of ureteral stent-related symptoms (SRSs) and compare it with that of solifenacin monotherapy and combined therapy of tamsulosin and silifenacin. Randomized controlled trials (RCTs), which evaluated the effectiveness of tamsulosin for the treatment of SRSs, were searched from the databases PubMed, EMBASE and the Cochrane Library published up to November 2018. Eight RCTs involving 1087 participants were finally included in this meta-analysis. The results showed that tamsulosin monotherapy could significantly decrease the urinary symptoms [mean difference (MD) -7.56, 95% confidence interval (CI) (-11.47, -3.65), P=0.0001] and body pain [MD -5.25, 95% CI (-8.03, -2.46), P=0.0002], and improve the sexual performance [MD -1.06, 95% CI (-1.89, -0.24), P=0.01] compared with the control group. Moreover, there was no significant difference between tamsulosin monotherapy and solifenacin monotherapy in all outcomes except for significantly better sexual performance in solifenacin group [MD 0.29, 95% CI (0.06, 0.51), P=0.01]. In addition, the effectiveness of combined therapy of tamsulosin and solifenacin was not superior to that of tamsulosin monotherapy. Our study demonstrated that tamsulosin monotherapy was effective for the treatment of patients with SRSs; evident superiority could not be found for therapy of tamsulosin and solifenacin combined.

Indexed as

Adrenergic alpha-1 Receptor AntagonistsDrug Therapy, CombinationFemaleHumansLower Urinary Tract SymptomsMaleRandomized Controlled Trials as TopicSolifenacin SuccinateStentsTamsulosinTreatment OutcomeUreteral DiseasesUrological AgentsAdrenergic alpha-1 Receptor AntagonistsSolifenacin SuccinateTamsulosinUrological Agentsmeta-analysissolifenacintamsulosinureteral stent-related symptoms

Identifiers

PMID31612387
OpenAlexW2980739868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.