Evidence map›Paper›PMID 31612144›Full record

ArticleBioMed research international2019

White Ginseng Ameliorates Depressive Behavior and Increases Hippocampal 5-HT Level in the Stressed Ovariectomized Rats.

Daehyuk Jang, Hyun-Ju Lee, Kyungjun Lee, Kyu-Ri Kim, Ran Won, Seung Eun Lee, Insop Shim

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. A Review of the Mechanisms and Risks ofDiseases (Basel, Switzerland) · 2025
    Review
  2. Review
  3. Review
  4. Effectiveness and Tolerability of Korean Red Ginseng Augmentation in Major Depressive Disorder Patients with Difficult-to-treat in Routine Practice.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2020
    Article
  5. Effects of Ginseng on Neurological Disorders.Frontiers in cellular neuroscience · 2020
    Review
  6. Antimania-Like Effect ofBioMed research international · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Daehyuk JangDepartment of Physiology, College of Medicine, Kyung Hee University, Seoul 02435, Republic of Korea.
Hyun-Ju LeeDepartment of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul 02435, Republic of Korea.ORCID 0000-0003-1067-2911
Kyungjun LeeDepartment of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul 02435, Republic of Korea.
Kyu-Ri KimDepartment of East West Medical Science, Graduate School of East-West Medical Science, Kyung Hee University, Kyunggi-do 17104, Republic of Korea.
Ran WonDepartment of Biomedical Laboratory Science, Division of Health Sciences, Dongseo University, Busan 47011, Republic of Korea.
Seung Eun LeeDepartment of Herbal Crop Research, NIHHS, RDA, Eumsung 27709, Republic of Korea.ORCID 0000-0003-1511-3262
Insop ShimDepartment of Physiology, College of Medicine, Kyung Hee University, Seoul 02435, Republic of Korea.ORCID 0000-0002-8014-9782
Kyung Hee University · KRDongseo University · KRKyung Hee University East-West Neo Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postmenopausal depression is closely associated with depletion of estrogen which modulates transmission of 5-HT, a key neurotransmitter that regulates stress-managing circuits in the brain. In this study, antidepressive efficacy of white ginseng (

Indexed as

AnimalsAntidepressive AgentsBrainDepressionDepressive DisorderDisease Models, AnimalHindlimb SuspensionHippocampusHumansPanaxRatsSerotoninStress, PsychologicalSwimmingAntidepressive AgentsSerotonin

Identifiers

PMID31612144
PMCPMC6755295
OpenAlexW2912802097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.