Evidence map›Paper›PMID 31612139›Full record

ArticleFrontiers in nutrition2019

Increased Posterior Cingulate Functional Connectivity Following 6-Month High-Dose B-Vitamin Multivitamin Supplementation: A Randomized, Double-Blind, Placebo-Controlled Trial.

Luke A Downey, Tamara N Simpson, Talitha C Ford, Grace McPhee, Chao Suo, Stephen P Myers, Chris Oliver, Con K K Stough

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Luke A DowneyFaculty of Health, Arts and Design, Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, VIC, Australia.
Tamara N SimpsonFaculty of Health, Arts and Design, Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, VIC, Australia.
Talitha C FordFaculty of Health, Arts and Design, Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, VIC, Australia.
Grace McPheeFaculty of Health, Arts and Design, Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, VIC, Australia.
Chao SuoBrain and Mental Health Laboratory, School of Psychological Sciences, Monash Institute of Cognitive and Clinical Neuroscience, Monash University, Clayton, VIC, Australia.
Stephen P MyersNatMed-Research, Division of Research, Southern Cross University, Lismore, NSW, Australia.
Chris OliverOliver Nutrition, Pty Ltd, Lismore, NSW, Australia.
Con K K StoughFaculty of Health, Arts and Design, Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, VIC, Australia.
Swinburne University of Technology · AULismore Base Hospital · AUMonash University · AUSouthern Cross University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

B vitamins are essential for optimal brain and body function, and are particularly important for cortical metabolic processes that have downstream effects on mitigating oxidative stress. Oxidative stress has been linked to poor psychological outcomes including psychological distress, which has wide-reaching implications for the community and the workplace. Given work-related stress has been associated with poor mental health outcomes, high-dose B vitamin supplementation may be effective in improving brain function and psychological outcomes via attenuation of oxidative stress. This randomized, double-blind, placebo-controlled study investigated psychological outcomes following 6-month supplementation of a high-B-vitamin multivitamin in a large sample of healthy adults (

Indexed as

default mode networkfunctional connectivitymultivitaminresting statestressvitamin B

Identifiers

PMID31612139
PMCPMC6776972
OpenAlexW2975227719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.