ReviewFrontiers in bioengineering and biotechnology2019
Enzymatic Modifications of Chitin, Chitosan, and Chitooligosaccharides.
Review in Frontiers in bioengineering and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
104 citing papers in PubMed, 395 citations in OpenAlex.
- Complete genome sequence ofMicrobiology resource announcements · 2026Article
- Chitosan-Based Hydrogels in Vascular Tissue Engineering Applications.Materials (Basel, Switzerland) · 2026Review
- Comparative Review of Microbial Chitosanases: Properties, Structures, Hydrolytic Modes and Applications.Current microbiology · 2026Review
- Unveiling Species Diversity Within Early-Diverging Fungi from China XIII: Four New Species ofMicroorganisms · 2026Article
- Green bioconversion of insoluble chitin: chitinase development pathways via multi-strategy synergy.Bioresources and bioprocessing · 2026Review
- Article
- Unveiling species diversity within early-diverging fungi from China XV: Three new species of Cunninghamellaceae (Mucorales).MycoKeys · 2026Article
- Article
- Recent advances of MXene/chitosan nanocomposites for industrial applications.Discover nano · 2025Review
- Characterization of the Chaetae Autofluorescence in the Earthworm Eisenia foetida and their Role in Locomotion.Journal of fluorescence · 2025Article
- Modified Polysaccharides: Potential Biomaterials for Bioprinting.Journal of functional biomaterials · 2025Review
- Optimizing Submerged Fermentation Conditions of Aspergillus niger for Chitin Production.Applied biochemistry and biotechnology · 2025Article
- Marine-Origin Polysaccharides and Their Chemically Modified Derivatives as Sources of Advanced Biofunctional Materials for Biomedical Applications.Biomacromolecules · 2025Review
- Functionalized chitosan as nano-delivery platform for CRISPR-Cas9 in cancer treatment.Asian journal of pharmaceutical sciences · 2025Review
- Green Processes for Chitin and Chitosan Production from Insects: Current State, Challenges, and Opportunities.Polymers · 2025Review
- Synthesis and Characterization of Magnesium Oxide-Enhanced Chitosan-Based Hemostatic Gels with Antibacterial Properties: Role of Amino Acids and Crosslinking.Molecules (Basel, Switzerland) · 2025Article
- Genome-Wide Mining of Chitinase Diversity in the Marine DiatomMarine drugs · 2025Article
- Unveiling species diversity within early-diverging fungi from China IV: Four new species ofMycoKeys · 2025Article
- Exploring the diversity and genomics of cultivableFrontiers in microbiology · 2025Article
- Characterization of extracellular chitin deacetylase fromCurrent research in microbial sciences · 2025Article
44 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chitin and its N-deacetylated derivative chitosan are two biological polymers that have found numerous applications in recent years, but their further deployment suffers from limitations in obtaining a defined structure of the polymers using traditional conversion methods. The disadvantages of the currently used industrial methods of chitosan manufacturing and the increasing demand for a broad range of novel chitosan oligosaccharides (COS) with a fully defined architecture increase interest in chitin and chitosan-modifying enzymes. Enzymes such as chitinases, chitosanases, chitin deacetylases, and recently discovered lytic polysaccharide monooxygenases had attracted considerable interest in recent years. These proteins are already useful tools toward the biotechnological transformation of chitin into chitosan and chitooligosaccharides, especially when a controlled non-degradative and well-defined process is required. This review describes traditional and novel enzymatic methods of modification of chitin and its derivatives. Recent advances in chitin processing, discovery of increasing number of new, well-characterized enzymes and development of genetic engineering methods result in rapid expansion of the field. Enzymatic modification of chitin and chitosan may soon become competitive to conventional conversion methods.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.