Evidence map›Paper›PMID 31612120›Full record

ArticleFrontiers in pediatrics2019

A Novel Mutation in the

Jose Antonio Tavares de Albuquerque, Alessandra Miramontes Lima, Edgar Borges de Oliveira Junior, Edson Kiyotaka Ishizuka, Walmir Cutrim Aragão-Filho, Nuria Bengala Zurro, Sônia Mayumi Chiba, Fátima Rodrigues Fernandes, Antonio Condino-Neto

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jose Antonio Tavares de AlbuquerqueImmunogenic Inc, São Paulo, Brazil.
Alessandra Miramontes LimaPENSI Institute - Jose Luiz Egydio Setubal Foundation, Sabará Hospital, São Paulo, Brazil.
Edgar Borges de Oliveira JuniorImmunogenic Inc, São Paulo, Brazil.
Edson Kiyotaka IshizukaPENSI Institute - Jose Luiz Egydio Setubal Foundation, Sabará Hospital, São Paulo, Brazil.
Walmir Cutrim Aragão-FilhoPENSI Institute - Jose Luiz Egydio Setubal Foundation, Sabará Hospital, São Paulo, Brazil.
Nuria Bengala ZurroDepartment of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Sônia Mayumi ChibaSabará Hospital, São Paulo, Brazil.
Fátima Rodrigues FernandesPENSI Institute - Jose Luiz Egydio Setubal Foundation, Sabará Hospital, São Paulo, Brazil.
Antonio Condino-NetoDepartment of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Fundação Instituto de Pesca do Estado do Rio de Janeiro · BRUniversidade de São Paulo · BRHospital São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic granulomatous disease (CGD) is an inherited, genetically heterogeneous disease characterized by defective phagocytic cell microbicidal function, leading to increased susceptibility to bacterial and fungal infections. CGD is caused by mutations in components of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase system, which is responsible for reactive oxygen species production during phagocytosis. Mutations in the neutrophil cytosolic factor 2 (

Indexed as

chronic granulomatous diseaseinterferon-gammaNADPH oxidaseNCF2 genenovel mutation

Identifiers

PMID31612120
PMCPMC6776604
OpenAlexW2977105940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.